35404-71-8

Basic information

• Product Name: N-METHYLAMINOMETHYL PHOSPHONIC ACID
• Synonyms: N-METHYLAMINOMETHYL PHOSPHONIC ACID;N-METHYLAMINOMETHYLPHOSPHONATE;Nsc 244826;[(MethylaMino)Methyl] Phosphonic Acid
• CAS NO: 35404-71-8
• Molecular Formula: C₂H₈NO₃P
• Molecular Weight: 125.06
• Product Categories: Amines;Impurities;Phosphorylating and Phosphitylating Agents
• Mol File: 35404-71-8.mol

Chemical Properties

• Boiling Point: 301.1°Cat760mmHg
• Flash Point: 135.9°C
• Appearance: /
• Density: 1.396g/cm³
• Vapor Pressure: 0.000252mmHg at 25°C
• Refractive Index: 1.467
• Storage Temp.: Refrigerator
• Solubility: Water (Slightly)
• CAS DataBase Reference: N-METHYLAMINOMETHYL PHOSPHONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYLAMINOMETHYL PHOSPHONIC ACID(35404-71-8)
• EPA Substance Registry System: N-METHYLAMINOMETHYL PHOSPHONIC ACID(35404-71-8)

Safety Data

• Hazardous Substances Data: 35404-71-8(Hazardous Substances Data)

Usage

Uses

An impurity of Glyphosate (G765000).

InChI:InChI=1/C2H8NO3P/c1-3-2-7(4,5)6/h3H,2H2,1H3,(H2,4,5,6)

Upstream product

• 5994-61-6 phosphonomethylimino-di-acetic acid 

Downstream Products

• 124725-27-5 N-(3'-Acetylamino-4'-methoxyphenylsulfonyl)-N-methylaminomethylphosphonic acid 

Relevant articles and documents

PROCESS FOR OXIDATION OF N-(PHOSPHONOMETHYL)IMINODIACETIC ACID

An oxidation catalyst is prepared by pyrolyzing a source of iron and a source of nitrogen on a carbon support. Preferably, a noble metal is deposited over the modified support which comprises iron and nitrogen bound to the carbon support. The catalyst is effective for oxidation reactions such as the oxidative cleavage of tertiary amines to produce secondary amines, especially the oxidation of N-(phosphonomethyl)iminodiacetic acid to N-(phosphonomethyl)-glycine.

Homogeneous catalysts for selective molecular oxygen driven oxidative decarboxylations

Cobalt(II) ion has been found to catalyze the molecular oxygen driven oxidation of N-(phosphonomethyl)iminodiacetic acid (PMIDA) to N-(phosphonomethyl)glycine (PMG) in aqueous solution.1 This homogeneous catalytic conversion is novel and represents, in effect, an oxidative dealkylation of one carboxymethyl moiety yielding the N-substituted glycine. The reaction is selective to the desired product PMG when carried out at the natural pH of the free acid substrate (～ 1-2) and when carried out at substrate loadings less than 5% by weight. In addition, the catalytic system is selective for the PMIDA substrate; i.e., other closely related ligands show no reactivity, e.g., NTA, EDTA, etc. The results of kinetic and mechanistic studies on dilute systems are presented and discussed with special emphasis on how an understanding of the mechanism can make it possible to generate a catalyst system that gives high yields even with high substrate loadings. The reactions are first-order in substrate and [Co]t. The oxygen pressure dependence exhibits saturation kinetics, while the selectivity increases as oxygen pressure increases. The rate is also inversely proportional to [H+]. The high selectivity of the oxidation and the unique selectivity of the cobalt catalytic system for the PMIDA substrate are discussed in terms of the magnitude of the metal ligand binding constant at the low pH of the reaction.