Methylaminomethylphosphonic acid

Base Information

• Chemical Name: Methylaminomethylphosphonic acid
• CAS No.: 35404-71-8
• Molecular Formula: C2H8NO3P
• Molecular Weight: 125.064
• NSC Number: 244826
• UNII: UUS34YQ2S5
• DSSTox Substance ID: DTXSID90865766
• Nikkaji Number: J1.090.729B
• Mol file: 35404-71-8.mol

Synonyms:35404-71-8;methylaminomethylphosphonic acid;[(methylamino)methyl]phosphonic acid;N-Methylaminomethylphosphonic acid;N-METHYLAMINOMETHYL PHOSPHONIC ACID;[(Methylamino)methyl] Phosphonic Acid;NSC 244826;((Methylamino)methyl)phosphonic acid;UUS34YQ2S5;NSC-244826;P-[(Methylamino)methyl]phosphonic Acid;UNII-UUS34YQ2S5;SCHEMBL64851;DTXSID90865766;GEO-04491;MFCD01332171;NSC244826;STL141043;AKOS003599788;AS-7017;(METHYLAMINO)METHYLPHOSPHONIC ACID;Phosphonic acid, P-[(methylamino)methyl]-;CS-0357068;FT-0671474;1-(4-Trifluoromethyl-biphenyl-4-yl)-ethanone;A924487

Chemical Property of Methylaminomethylphosphonic acid

Chemical Property:

• Vapor Pressure: 0.000252mmHg at 25°C
• Melting Point: >270°C (dec.)
• Boiling Point: 301.1°Cat760mmHg
• Flash Point: 135.9°C
• PSA: 79.37000
• Density: 1.396g/cm³
• LogP: -0.26810
• Storage Temp.: Refrigerator
• Solubility.: Water (Slightly)
• XLogP3: -4.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 125.02418011
• Heavy Atom Count: 7
• Complexity: 86.9

Purity/Quality:

99% ^*data from raw suppliers

[(Methylamino)methyl]PhosphonicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNCP(=O)(O)O
• Uses: An impurity of Glyphosate (G765000).

Technology Process of Methylaminomethylphosphonic acid

There total 2 articles about Methylaminomethylphosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphonomethylimino-di-acetic acid (5994-61-6) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + formic acid (64-18-6) + Aminomethylphosphonic acid (1066-51-9) + N-methylaminomethanephosphonic acid (35404-71-8) + N-methyl N-phosphonomethylglycine (24569-83-3) + N-(phosphonemethyl)glycine (1071-83-6) + Phosphate (14265-44-2,264888-19-9)

Guidance literature:

With oxygen; In water; at 100 ℃; Reagent/catalyst; Flow reactor;

Reference yield:

phosphonomethylimino-di-acetic acid (5994-61-6) → formic acid (64-18-6) + Aminomethylphosphonic acid (1066-51-9) + N-methylaminomethanephosphonic acid (35404-71-8) + N-(phosphonemethyl)glycine (1071-83-6) + N-formyl-N-(phosphonomethyl)glycine (84767-96-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7)

Guidance literature:

With cobalt(II) sulfate; oxygen; In water; at 85 ℃; under 41371.8 Torr; Product distribution; Rate constant; Mechanism; var. temp., pressure and reagents; deuterium isotope effect;

DOI:10.1021/ja00009a023

Reference yield:

N-methylaminomethanephosphonic acid (35404-71-8) + 2-methoxyacetanilide (93-26-5) → N-(3'-Acetylamino-4'-methoxyphenylsulfonyl)-N-methylaminomethylphosphonic acid (124725-27-5)

Guidance literature:

With hydrogenchloride; chlorosulfonic acid; sodium hydroxide; In water;

upstream raw materials:

phosphonomethylimino-di-acetic acid

Downstream raw materials:

N-(3'-Acetylamino-4'-methoxyphenylsulfonyl)-N-methylaminomethylphosphonic acid

Refernces

• 1、 Riley, Dennis P.,Fields, Donald L.,Rivers, Willie. "Homogeneous catalysts for selective molecular oxygen driven oxidative decarboxylations". . p. 3371 - 3378. Retrieved 2007/10/02.