354153-39-2Relevant academic research and scientific papers
Asymmetric synthesis of the four possible fagomine isomers
Takahata, Hiroki,Banba, Yasunori,Ouchi, Hidekazu,Nemoto, Hideo,Kato, Atsushi,Adachi, Isao
, p. 3603 - 3607 (2003)
The asymmetric synthesis of fagomine and its congeners 1-4 has been achieved by catalytic ring-closing metathesis (RCM). The synthesis involved the construction of the piperidene-type chiral building block 5 followed by dihydroxylation, starting from the D-serine-derived Garner aldehyde 6.
Asymmetric synthesis of fagomine and its congeners
Banba, Yasunori,Abe, Chiemi,Nemoto, Hideo,Kato, Atsushi,Adachi, Isao,Takahata, Hiroki
, p. 817 - 819 (2007/10/03)
The total synthesis of fagomine and its congeners 1-3 has been achieved starting from D-serine-derived Garner aldehyde 5 by catalytic ring-closing metathesis (RCM) for the construction of the piperidine ring followed by dihydroxylation.
