35418-58-7 Usage
Uses
Used in Pharmaceutical Industry:
1-PalMitoyl-2-arachidoyllecithin is used as a key component in the preparation of auto-oxidized phospholipid for electrospray ionization mass spectroscopic (ESI-MS) analysis. This application helps researchers understand the molecular interactions and properties of oxidized phospholipids, which are involved in chronic inflammation and vascular disease.
Used in Diagnostics:
In the field of diagnostics, 1-PalMitoyl-2-arachidoyllecithin is used as a crucial component in liposome preparation for the treatment of organoids as an antigen in enzyme-linked immunosorbent assay (ELISA). This application aids in the detection of autoantibodies to phospholipids, which can be indicative of various autoimmune diseases, such as hypertension and myocardial infarction.
Used in Research:
1-PalMitoyl-2-arachidoyllecithin is also used in research studies to investigate the role of oxidized phospholipids in chronic inflammation and vascular disease. By studying the signaling pathways and molecular interactions of PAPC, researchers can gain insights into the underlying mechanisms of these conditions and potentially develop novel therapeutic strategies.
Biochem/physiol Actions
Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
Check Digit Verification of cas no
The CAS Registry Mumber 35418-58-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,1 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 35418-58:
(7*3)+(6*5)+(5*4)+(4*1)+(3*8)+(2*5)+(1*8)=117
117 % 10 = 7
So 35418-58-7 is a valid CAS Registry Number.
35418-58-7Relevant academic research and scientific papers
Synthesis of a small library of mixed-acid phospholipids from D-mannitol as a homochiral starting material
Xia, Jie,Hui, Yong-Zheng
, p. 1659 - 1663 (2007/10/03)
Synthesis of a series of mixed-acid phospholipids containing a polyunsaturated fatty acid using a newly protecting strategy are described. Thus, benzyl and methyl α-(2,4-dinitrophenyl)acetic acid which were respectively removed by BCl3 and 354 nm light are used as protecting groups.
