35432-75-8

Basic information

• Product Name: tert-butyl 2-methylpentaneperoxoate
• Synonyms: pentaneperoxoic acid, 2-methyl-, 1,1-dimethylethyl ester; tert-Butyl 2-methylpentaneperoxoate
• CAS NO: 35432-75-8
• Molecular Formula: C₁₀H₂₀O₃
• Molecular Weight: 188.26
• Mol File: 35432-75-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 209.1°C at 760 mmHg
• Flash Point: 62.3°C
• Density: 0.923g/cm³
• Vapor Pressure: 0.207mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: tert-butyl 2-methylpentaneperoxoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-methylpentaneperoxoate(35432-75-8)
• EPA Substance Registry System: tert-butyl 2-methylpentaneperoxoate(35432-75-8)

Safety Data

• Hazardous Substances Data: 35432-75-8(Hazardous Substances Data)

Upstream product

• 75-91-2 tert.-butylhydroperoxide 
• 97-61-0 2-Methylpentanoic acid 

Downstream Products

• 93194-81-1 2-(pentan-2-yl)benzo[d]thiazole 

Relevant articles and documents

Iron-Catalyzed Dehydrative Alkylation of Propargyl Alcohol with Alkyl Peroxides to Form Substituted 1,3-Enynes

This paper reports a new method for the generation of substituted 1,3-enynes, whose synthesis by other methods could be a challenge. The dehydrative decarboxylative cascade coupling reaction of propargyl alcohol with alkyl peroxides is enabled by an iron catalyst and alkylating reagents. Primary, secondary, and tertiary alkyl groups can be introduced into 1,3-enynes, affording various substituted 1,3-enynes in moderate to good yields. Mechanistic studies suggest the involvement of a radical-polar crossover pathway.

Iron-catalyzed C-H alkylation of heterocyclic C-H bonds

An efficient, iron-catalyzed C-H alkylation of benzothiazoles by using alkyl diacyl peroxides and alkyl tertbutyl peresters which are readily accessible from carboxylic acids to synthesize 2-alkylbenzothiazoles is developed. This reaction is environmentally benign and compatible with a broad range of functional groups. Various primary, secondary, and tertiary alkyl groups can be efficiently incorporated into diverse benzothiazoles. The effectiveness of this method is illustrated by late-stage functionalization of biologically active heterocycles.