35433-52-4Relevant articles and documents
Palladium-catalyzed suzuki-miyaura cross-coupling of a-halomethyl oxime ethers and site-selective cross-coupling of dihalo derivatives
Noverges, Barbara,Mollar, Cristian,Medio-Simon, Mercedes,Asensio, Gregorio
supporting information, p. 2327 - 2342 (2013/10/01)
The cross-coupling reaction of chloro- and bromomethyl oxime ethers with a wide range of aryl-, heteroaryl- and vinylboronic acids in the presence of catalytic palladium complexes with different phosphines has been carried out with good yields (60-98%, 40 examples). Regioselective cross-coupling reactions differentiating between an alkyl or aryl position are achieved from dihalo oxime ethers containing Csp2- and Csp3-halogen bonds using mono- or dicoordinated palladium catalysts such as Pd (dba)2/P (o-tolyl)3 or Pd (PPh3)4. The selective orthogonal functionalization of dihalo oxime ethers is also described. Site-selective transformations allow the introduction of the biaryl motif into dihalo oxime ethers preserving the highly activated alkyl halide moiety vicinal to the oxime group for further transformations. In this context, Z- and E-oxime ethers could be considered as synthetic equivalents of ketones in palladium-catalyzed Suzuki reactions.
Certain oxime esters
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, (2008/06/13)
Compounds having the formula EQU1 in which X is chlorine or bromine, R is hydrogen or alkyl having from 1 to 6 carbon atoms; R1 is alkyl having 1 to 4 carbon atoms or haloalkyl having from 1 to 4 carbon atoms; phenyl or nuclear substituted derivatives thereof in which the substituents are halogen, nitro or lower alkyl, R2 is alkyl having from 1 to 6 carbon atoms or haloalkyl having from 1 to 6 carbon atoms. The compounds are useful in controlling weeds and for inhibiting the growth of bacteria and fungi.
