354512-22-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Methoxy-5-nitrobenzaldehyde is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure makes it a valuable component in the development of new drugs and biologically active compounds.
Used in Dye Industry:
In the dye industry, 3-Methoxy-5-nitrobenzaldehyde is utilized as a starting material for the preparation of other benzaldehyde derivatives. Its properties contribute to the creation of diverse dyes with specific characteristics.
Used as a Reagent in Organic Synthesis:
3-Methoxy-5-nitrobenzaldehyde also serves as a reagent in organic synthesis, playing a crucial role in various chemical reactions and processes.
Used in Antibacterial and Antifungal Applications:
Leveraging its antibacterial and antifungal properties, 3-Methoxy-5-nitrobenzaldehyde has potential applications in the development of new drugs and biologically active compounds, contributing to the advancement of treatments for various infections.

InChI:InChI=1/C8H7NO4/c1-13-8-3-6(5-10)2-7(4-8)9(11)12/h2-5H,1H3

Upstream product

• 78238-12-7 3-methoxy-5-nitrobenzoic acid 
• 2702-58-1 methyl 3,5-dinitrobenzoate 
• 33224-19-0 3-methoxy-5-nitrobenzonitrile 
• 78238-13-8 3-methoxy-5-nitrobenzoic acid methyl ester 
• 99-34-3 3,5-dinitrobenzoic acid 
• 354525-36-3 (3-methoxy-5-nitrophenyl)methanol 

Downstream Products

• 1325235-97-9 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2S)-2-(cyclohexanecarboxamido)propanoate 
• 1325235-98-0 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl 2-(cyclohexanecarboxamido)acetate 
• 1325235-99-1 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-acetamidopropanoate 
• 1325236-01-8 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-(cyclopentanecarboxamido)propanoate 
• 1325236-02-9 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-(cyclohexanecarboxamido)-3-methylbutanoate 
• 1325236-03-0 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-(cyclohexanecarboxamido)-4-methylpentanoate 
• 1325236-04-1 (4R,7E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-(cyclohexanecarboxamido)-3-phenylpropanoate 
• 1325235-67-3 C₁₀H₁₃NO₄ 
• 1325235-69-5 3-(3-amino-5-methoxyphenyl)propan-1-ol 
• 1325235-70-8 N-(3-(3-hydroxypropyl)-5-methoxyphenyl)non-8-enamide 
• 1325235-75-3 (S,E)-N-(3-(7-hydroxy-4-methyldeca-3,9-dien-1-yl)-5-methoxyphenyl)non-8-enamide 
• 1325235-76-4 (R)-(R,E)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl 2-(cyclohexanecarboxamido)propanoate 
• 1325235-78-6 (4R,7Z)-10-(3-methoxy-5-(non-8-enamido)phenyl)-7-methyldeca-1,7-dien-4-yl (2R)-2-(cyclohexanecarboxamido)propanoate 
• 1325235-93-5 N-(3-(3-iodopropyl)-5-methoxyphenyl)non-8-enamide 

Relevant academic research and scientific papers

Structure-activity relationship of 7-aryl-2-anilino-pyrrolopyrimidines as Mer and Axl tyrosine kinase inhibitors

The TAM (Axl, Mer, and Tyro3) family is implicated in the survival and chemoresistance of tumours and has emerged as a potential therapeutic target. A novel series of 7-aryl-2-anilino-pyrrolopyrimidines were identified as potent Axl/Mer tyrosine kinase in

Design, synthesis, and biological evaluation of m-amidophenol derivatives as a new class of antitubercular agents

A series of m-amidophenol derivatives (6a-6l, 7a-7q, 9a, 9b, 12a-12c, 14 and 15) were designed and synthesized. Their antitubercular activities were evaluated in vitro against M. tuberculosis strains H37Ra and H37Rv and clinically isolated multidrug-resistant M. tuberculosis strains. Ten compounds displayed minimal inhibitory concentrations (MICs) against M. tuberculosis H37Ra below 2.5 μg mL?1 and 6g was the most active compound (MIC = 0.625 μg mL?1). Compounds 6g and 7a also showed potent inhibitory activity against M. tuberculosis H37Rv (MIC = 0.39 μg mL?1) and several clinically isolated multidrug-resistant M. tuberculosis strains (MIC = 0.39-3.125 μg mL?1). The compounds did not show inhibitory activity against normal Gram-positive and Gram-negative bacteria. They exhibited low cytotoxicity against HepG2 and RAW264.7 cell lines. The results demonstrated m-amidophenol as an attractive scaffold for the development of new antitubercular agents.

PHENYL-UREA AND PHENYL-CARBAMATE DERIVATIVES AS INHIBITORS OF PROTEIN AGGREGATION

The present invention relates to certain phenyl-urea and phenyl-carbamate derivatives, pharmaceutical compositions containing them, and methods of using them, including methods for preventing, reversing, slowing, or inhibiting protein aggregation, and methods of treating diseases that are associated with protein aggregation, including neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, Lewy body disease, and multiple system atrophy.

Monoenomycin: A simplified trienomycin A analogue that manifests anticancer activity

Macrocyclic natural products are a powerful class of leadlike chemical entities. Despite commonly violating Lipinski's "rule of 5", these compounds often demonstrate superior druglike physicochemical and pharmacokinetic attributes when compared to their acyclic counterparts. However, the elaborate structural architectures of such molecules require rigorous synthetic investigation that complicates analogue development and their application to drug discovery programs. To circumvent these limitations, a conformation-based approach using limited structure-activity relationships and molecular modeling was implemented to design simplified analogues of trienomycin A, in which the corresponding analogues could be prepared in a succinct manner to rapidly identify essential structural components necessary for biological activity. Trienomycin A is a member of the ansamycin family of natural products that possesses potent anticancer activity. These studies revealed a novel trienomycin A analogue, monoenomycin, which manifests potent anticancer activity.

Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents

A new series of 3-aminobenzophenone compounds as potent inhibitors of tubulin polymerization was discovered based on the mimic of the aminocombretastatin molecular skeleton. Lead compounds 5 and 11, with alkoxy groups at the C-4 position of B-ring, were p