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1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine, which is produced by the oxidation of the primary metabolite, N-methylhistamine. It is generated by mast cells and plays a role in the inflammatory response. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.

35454-39-8

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35454-39-8 Usage

Uses

Used in Pharmaceutical Industry:
1-Methyl-4-imidazoleacetic Acid Hydrochloride is used as a chemical intermediate for the synthesis of N-[1-(9,10-methano-9-anthracenylmethyl)-4-piperidinyl]alkanamides and analogs. These compounds serve as dopamine D2 receptor antagonists, which have potential applications in the treatment of various neurological and psychiatric disorders.
Used in Diagnostics:
1-Methyl-4-imidazoleacetic Acid Hydrochloride is used as a biomarker for histamine secretion. The measurement of MIMA levels in urine helps in the evaluation of histamine release, which is particularly relevant in the context of systemic mastocytosis, a condition characterized by the abnormal growth of mast cells in the body.

Check Digit Verification of cas no

The CAS Registry Mumber 35454-39-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,5 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 35454-39:
(7*3)+(6*5)+(5*4)+(4*5)+(3*4)+(2*3)+(1*9)=118
118 % 10 = 8
So 35454-39-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O2.ClH/c1-8-3-5(7-4-8)2-6(9)10;/h3-4H,2H2,1H3,(H,9,10);1H

35454-39-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-METHYL-4-IMIDAZOLEACETIC ACID HYDROCHLORIDE

1.2 Other means of identification

Product number -
Other names 1-methyl-4-imidazole acetic acid hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35454-39-8 SDS

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