35456-48-5

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 108-95-2 phenol 
• 115044-08-1 3-(4-hydroxyphenyl)-2-methylpropionitrile 
• 113277-24-0 (E)-3-(4-hydroxyphenyl)-2-methyl-prop-2-enoic acid 

Downstream Products

• 81579-29-5 methyl 3-(4-hydroxyohenyl)-2-methylpropionate 
• 115044-10-5 3-(4-hydroxyphenyl)-2-methylpropanoyl-Met-Gly-Trp-Met-Asp-Phe-NH₂ 
• 115044-11-6 3-(4-hydroxyphenyl)-2-methylpropanoyl-Nle-Gly-Trp-Met-Asp-Phe-NH₂ 
• 857903-60-7 methyl 3-{4-[(7-chloro-2-quinoxalinyl)oxy]phenyl}-2-methylpropionate 
• 115060-17-8 suciinimidyl 3-(4-hydroxyphenyl)-2-methylpropanoate 
• 138460-13-6 β-(3,5-diiodo-4-hydroxyphenyl)-α-methylpropionic acid 

Relevant academic research and scientific papers

Enantioselective Enzymatic Reduction of Acrylic Acids

An ene-reductase (ERED 36) with broad substrate specificity was identified, and optimization studies led to the development of an enzymatic protocol for the reduction of α,β-unsaturated acids under mild, aqueous conditions. The substrate scope includes aromatic- A nd aliphatic-substituted acrylic acids, as well as cyclic α,β-substituted acrylic acids, yielding chiral α-substituted acids with exquisite levels of enantioselectivity (>99% ee).

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4

The criteria for the activity of 2-{4-[(7-chloro-2-quinoxalinyl)oxy] phenoxy}propionic acid (XK469) and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy} propionic acid (SH80) against transplanted tumors in mice established in previous studies, require a (7-halo-2