354561-70-9 Usage
Uses
Used in Medicinal Chemistry:
2-CHLORO-5-OXAZOLO[4,5-B]PYRIDIN-2-YL-PHENYLAMINE is used as a ligand in medicinal chemistry for its ability to interact with different biological targets. Its unique structure allows it to bind selectively, making it a valuable tool in the discovery and development of new pharmaceuticals.
Used in Drug Development:
In the pharmaceutical industry, 2-CHLORO-5-OXAZOLO[4,5-B]PYRIDIN-2-YL-PHENYLAMINE serves as a key component in drug development. Its potential to modulate biological activity and target specific receptors makes it instrumental in creating effective treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 354561-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,4,5,6 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 354561-70:
(8*3)+(7*5)+(6*4)+(5*5)+(4*6)+(3*1)+(2*7)+(1*0)=149
149 % 10 = 9
So 354561-70-9 is a valid CAS Registry Number.
354561-70-9Relevant academic research and scientific papers
3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis
Ferrins, Lori,Rahmani, Rapha?l,Sykes, Melissa L.,Jones, Amy J.,Avery, Vicky M.,Teston, Eliott,Almohaywi, Basmah,Yin, JieXiang,Smith, Jason,Hyland, Chris,White, Karen L.,Ryan, Eileen,Campbell, Michael,Charman, Susan A.,Kaiser, Marcel,Baell, Jonathan B.
, p. 450 - 465 (2013/10/01)
A whole organism high-throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei led to the recent discovery of several novel compound classes with low micromolar activity against this organism and without appreciable cytotoxici