354573-95-8Relevant academic research and scientific papers
Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties
Wrobleski, Stephen T.,Chen, Ping,Hynes Jr., John,Lin, Shuqun,Norris, Derek J.,Pandit, Chennagiri R.,Spergel, Steven,Wu, Hong,Tokarski, John S.,Chen, Xiaorong,Gillooly, Kathleen M.,Kiener, Peter A.,McIntyre, Kim W.,Patil-Koota, Vina,Shuster, David J.,Turk, Lori A.,Yang, Guchen,Leftheris, Katerina
, p. 2110 - 2116 (2007/10/03)
A series of unique indazoles and pyridoindolones have been rationally designed and synthesized as novel classes of cannabinoid ligands based on a proposed bioactive amide conformation. This has led to the discovery of the novel indolopyridone 3a as a conf
