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4-Bromoquinazoline, a brominated derivative of quinazoline with the molecular formula C8H5BrN2, is a heterocyclic compound that plays a significant role in pharmaceutical research and development. It is recognized for its diverse biological activities, including antifungal, antibacterial, and antitumor properties, and is valued for its applications in organic synthesis, drug scaffold preparation, and as an intermediate in the production of agrochemicals and fine chemicals.

354574-59-7

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354574-59-7 Usage

Uses

Used in Pharmaceutical Research and Development:
4-Bromoquinazoline is used as a key intermediate in the synthesis of novel drugs and potential therapeutic agents, leveraging its biological activities for the development of treatments targeting various diseases and conditions.
Used in Organic Synthesis:
As a building block in organic synthesis, 4-Bromoquinazoline is utilized for the preparation of diverse organic molecules, contributing to the creation of new chemical entities with potential applications across various industries.
Used in Agrochemical Production:
4-Bromoquinazoline serves as a valuable intermediate in the production of agrochemicals, playing a crucial role in the development of effective and targeted pest control solutions for the agricultural sector.
Used in Fine Chemicals Production:
Its role as an intermediate extends to the manufacturing of fine chemicals, where 4-Bromoquinazoline contributes to the synthesis of high-quality specialty chemicals for use in various applications, including but not limited to the fragrance, flavor, and pharmaceutical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 354574-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,4,5,7 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 354574-59:
(8*3)+(7*5)+(6*4)+(5*5)+(4*7)+(3*4)+(2*5)+(1*9)=167
167 % 10 = 7
So 354574-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2/c9-8-6-3-1-2-4-7(6)10-5-11-8/h1-5H

354574-59-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromoquinazoline

1.2 Other means of identification

Product number -
Other names Quinazoline,4-bromo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:354574-59-7 SDS

354574-59-7Downstream Products

354574-59-7Relevant academic research and scientific papers

Cl3CCN/PPh3 and CBr4/PPh3: Two efficient reagent systems for the preparation of N-heteroaromatic halides

Kijrungphaiboon, Woranun,Chantarasriwong, Oraphin,Chavasiri, Wainthorn

scheme or table, p. 674 - 677 (2012/02/15)

Cl3CCN/PPh3 and CBr4/PPh3 are two highly reactive reagent systems for the conversion of N-heteroaromatic hydroxy compounds into N-heteroaromatic chlorides or bromides in moderate to excellent yields under mild and acid-free conditions.

Application of phosphonium salts to the reactions of various kinds of amides

Sugimoto, Osamu,Mori, Miho,Moriya, Keisuke,Tanji, Ken-Ichi

, p. 1112 - 1118 (2007/10/03)

The phosphonium salts 1 and 2 prepared from triphenylphosphine and N-halogenosuccinimide proved to be applicable to the conversion of amide compounds. Especially, halogenation of electron-deficient heteroaromatic alcohols with these reagents seems to be a convenient method compared to the halogenation with phosphorus oxyhalides.

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