354581-67-2

Upstream product

• 354581-66-1 3',5'-bis(O-tert-butyldimethylsilyl)-2'-deoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxymethyl)-4-(N¹-1,2,4-triazolyl)uridine 
• 354581-65-0 3',5'-bis(O-tert-butyl-dimethylsilyl)-2'-deoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxymethyluridine 
• 244631-64-9 5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)oxymethyl-3',5'-di-O-tert-butyldimethylsilyl-N³-pivaloyloxymethyl-2'-deoxyuridine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 354581-70-7 N⁴-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxymethyl)cytidine 
• 354581-68-3 N⁴-benzoyl-2'-deoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxymethyl)cytidine 

Relevant academic research and scientific papers

Chemical and enzymatic synthesis of DNA fragments containing 5-(βD-glucopyranosyloxymethyl)-2′-deoxycytidine - A modified nucleoside in T4 phage DNA

DNA fragments 23 and 25, containing 5-hydroxymethyl-2′-deoxycytidine (5-HMdC) and 5-(β-D-glucopyranosyloxymethyl)-2′-deoxycytidine (5-GlcMdC) units, respectively, were assembled by means of a solid support-assisted synthesis using phosphoramidite building blocks 4 and 5, respectively. In addition, 20-mer 23 was converted into fragment 26 by a glycosylation with uridine diphosphoglucose (UDPG), catalyzed by T4 β-glucosyltransferase (BGT).