354582-93-7

Upstream product

• 31295-41-7 4,5-diamino-2,6-dimercaptopyrimidine 
• 113211-94-2 2,3-difluorobenzyl bromide 

Downstream Products

• 357612-93-2 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone 
• 1033902-89-4 C₂₀H₁₄F₄N₄S₂ 
• 354582-94-8 C₂₂H₁₇F₄N₅O₂S₂ 
• 415920-32-0 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7-pteridinamine 
• 415920-31-9 [[4-amino-2,6-bis[[(2,3-difluorophenyl)methyl]thio]-5-pyrimidinyl]amino]acetonitrile 

Relevant academic research and scientific papers

Evaluation of a series of bicyclic CXCR2 antagonists

The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat

7-amino-2-alkylthiopteridin-4-yl-amines for the treatment of chemokine-related diseases

Pteridine compounds of formula (I) in which R1, R2, R3 and R4 are as specified in the claims, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in t

Pyrimidine compounds and their use as modulators of chemokine receptor activity

The invention provides certain heterocyclic compounds, processes, and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy; in formula (I), A is a group of formula (a) or (b).