357612-93-2

Basic information

• Product Name: 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone
• Synonyms: 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone
• CAS NO: 357612-93-2
• Molecular Weight: 464.467
• Mol File: 357612-93-2.mol

Chemical Properties

• CAS DataBase Reference: 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone(357612-93-2)
• EPA Substance Registry System: 2,4-bis[[(2,3-difluorophenyl)methyl]thio]-7(8H)-pteridinone(357612-93-2)

Safety Data

• Hazardous Substances Data: 357612-93-2(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 31295-41-7 4,5-diamino-2,6-dimercaptopyrimidine 
• 113211-94-2 2,3-difluorobenzyl bromide 
• 354582-93-7 2,6-bis[[(2,3-difluorophenyl)methyl]thio]-4,5-pyrimidinediamine 

Downstream Products

• 357612-06-7 2-(2,3 difluoro-benzylsulphanyl)-4-((R)-2-hydroxy-1-methyl-ethylamino)-8H-pteridin-7-one 

Relevant articles and documents

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The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat

Pteridine compounds for the treatment of psoriasis

The invention provides pteridine compounds of formula (I), processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy. Formula (I) in which A is a group of formula (a) or (b).