35461-98-4

Basic information

• Product Name: 4-(2-FURYL)BENZOIC ACID
• Synonyms: Benzoic acid, 4-(2-furanyl)-;CHEMBRDG-BB 4003496;AKOS BAR-0073;4-FURAN-2-YL-BENZOIC ACID;4-(2-FURYL)BENZOIC ACID;RARECHEM AL BO 2309;4-Fur-2-ylbenzoic acid;4-(2-furyl)benzoic acid(SALTDATA: FREE)
• CAS NO: 35461-98-4
• Molecular Formula: C₁₁H₈O₃
• Molecular Weight: 188.18
• Mol File: 35461-98-4.mol
• Article Data: 20

Chemical Properties

• Melting Point: 231 °C
• Boiling Point: 345 °C at 760 mmHg
• Flash Point: 162.5 °C
• Appearance: /
• Density: 1.254 g/cm³
• Vapor Pressure: 2.41E-05mmHg at 25°C
• Refractive Index: 1.581
• PKA: 4.20±0.10(Predicted)
• CAS DataBase Reference: 4-(2-FURYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-FURYL)BENZOIC ACID(35461-98-4)
• EPA Substance Registry System: 4-(2-FURYL)BENZOIC ACID(35461-98-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26
• Hazardous Substances Data: 35461-98-4(Hazardous Substances Data)

Usage

General Description

4-(2-Furyl)benzoic acid is a homologous derivative of benzoic acid, recognised for its crucial role in industries, particularly in organic synthesis and pharmaceutical fields. The structure of the substance includes a furyl ring (a five-membered aromatic ring containing an oxygen atom) attached to the benzene core of benzoic acid. It often appears as a white solid at room temperature. Though information about its harmfulness to humans may be limited, like most chemicals, using protective clothing and handling with care is advised. Application of this chemical can be seen in different types of synthesis reactions and in producing specific compounds in pharmaceutical manufacturing.

InChI:InChI=1/C11H8O3/c12-11(13)9-5-3-8(4-6-9)10-2-1-7-14-10/h1-7H,(H,12,13)

Upstream product

• 619-58-9 4-iodobenzoic acid 
• 118486-94-5 2-(tributylstannyl)furan 
• 586-76-5 4-Bromobenzoic acid 
• 110-00-9 furan 
• 456-25-7 p-carboxyphenyl diazonium tetrafluoroborate 
• 150-13-0 4-amino-benzoic acid 
• 13331-23-2 fur-2-ylboronic acid 
• 81745-86-0 2-furylzinc chloride 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 497-19-8 sodium carbonate 

Relevant articles and documents

Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing

Optimization of benzamide PPARδ modulator 1 led to (E)-6-(2-((4-(furan-2-yl)-N-methylbenzamido)methyl)phenoxy)-4-methylhex-4-enoic acid (18), a potent selective PPARδ modulator with significantly improved exposure in multiple species following oral administration.

Effective bimetallic composite catalysts for the synthesis of arylated furans and thiophenes in aqueous media

[Figure not available: see fulltext.] N-(4,6-Dimethylpyrimidin-2-yl)-5-phenylisoxazole-3-carboxamide was used as a ligand for obtaining bimetallic boron-containing heterogeneous catalysts Pd–Ni(Co)–B–L (Ni(Co):Pd = 9:1). The obtained composites were highl

PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Provided herein are compounds of formula (I) useful for the treatment of PPAR-delta related diseases (e.g. mitochondrial diseases, muscular diseases, vascular diseases, demyelinating diseases and metabolic diseases).