456-25-7

Basic information

• Product Name: 4-carboxybenzediazonium tetrafluoroborate
• Synonyms: 4-carboxybenzediazonium tetrafluoroborate;Benzenediazonium, 4-carboxy-, tetrafluoroborate(1-)
• CAS NO: 456-25-7
• Molecular Formula: BF₄*C₇H₅N₂O₂
• Molecular Weight: 0
• Mol File: 456-25-7.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-carboxybenzediazonium tetrafluoroborate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-carboxybenzediazonium tetrafluoroborate(456-25-7)
• EPA Substance Registry System: 4-carboxybenzediazonium tetrafluoroborate(456-25-7)

Safety Data

• Hazardous Substances Data: 456-25-7(Hazardous Substances Data)

Usage

General Description

4-carboxybenzediazonium tetrafluoroborate is a chemical compound that consists of a benzene ring with a carboxylic acid group and a diazonium moiety. It is also known by its chemical formula C7H6BF4N2O2. 4-carboxybenzediazonium tetrafluoroborate is commonly used in organic synthesis as a versatile reagent for the preparation of azo dyes and pigments. Its tetrafluoroborate salt form makes it a stable and easily handled compound. Furthermore, it is also used in the production of pharmaceuticals and as an intermediate for the synthesis of various organic compounds. However, it should be handled with care due to its potential reactivity and toxicity.

Upstream product

• 540-80-7 tert.-butylnitrite 
• 150-13-0 4-amino-benzoic acid 
• 13755-29-8 sodium tetrafluoroborate 
• 7632-00-0 sodium nitrite 

Downstream Products

• 121725-02-8 4-p-carboxyphenylazo-1-isopropyl-2,2-dimethyl-1H-pyrrol-3(2H)-one 
• 115974-97-5 methyl (E)-4-carboxyl cinnamate 
• 117076-42-3 4-<2-(Methoxycarbonyl)ethenyl>benzoyl-chlorid 
• 874513-29-8 (C₆H₅)3SnC₆H₃(N(CH₃)2)NNC₆H₄COOH 
• 1386388-88-0 4-(phenyltellanyl)benzoic acid 
• 35461-98-4 4-(furan-2-yl)benzoic acid 
• 29886-62-2 4-thiophen-2-yl-benzoic acid 
• 669713-98-8 1-tert-butoxycarbonyl-2-(4-carboxyphenyl)pyrrole 
• 99-96-7 4-hydroxy-benzoic acid 
• 6427-66-3 4-azidobenzoic acid 
• 216955-64-5 4-(2H-tetrazol-2-yl)benzoic acid 
• 456-22-4 4-Fluorobenzoic acid 
• 138-41-0 4-(aminosulfonyl)-benzoic acid 

Relevant articles and documents

Aryl diazonium chemistry for the surface functionalization of glassy biosensors

Nanostring resonator and fiber-optics-based biosensors are of interest as they offer high sensitivity, real-time measurements and the ability to integrate with electronics. However, these devices are somewhat impaired by issues related to surface modification. Both nanostring resonators and photonic sensors employ glassy materials, which are incompatible with electrochemistry. A surface chemistry approach providing strong and stable adhesion to glassy surfaces is thus required. In this work, a diazonium salt induced aryl film grafting process is employed to modify a novel SiCN glassy material. Sandwich rabbit IgG binding assays are performed on the diazonium treated SiCN surfaces. Fluorescently labelled anti-rabbit IgG and anti-rabbit IgG conjugated gold nanoparticles were used as markers to demonstrate the absorption of anti-rabbit IgG and therefore verify the successful grafting of the aryl film. The results of the experiments support the effectiveness of diazonium chemistry for the surface functionalization of SiCN surfaces. This method is applicable to other types of glassy materials and potentially can be expanded to various nanomechanical and optical biosensors.

Method for preparing iodo-benzoic acid (ester) by improving moral Michael reaction

The invention discloses a method for preparing iodo-benzoic acid (ester) by improving a moral reaction, and belongs to the technical field of organic synthesis. The method comprises the following steps: preparing and separating the diazonium tetrafluoroborate through diazotization of aminobenzoic acid (ester) and then performing iodination reaction with the iodinated reagent in an organic medium to obtain the corresponding iodo carboxylic acid (ester). The iodo-benzoic acid (ester) prepared by the method has high purity. The method has the advantages of good quality and simple post-treatment, and the product yield reaches 70 - 90%.

Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation

Novel biomolecular conjugates containing non-natural aromatic chemical moieties covalently coupled to a diazonium compound and methods of their use are disclosed.

Method and manufacturing method thereof and a metal particulate carrier org. compd.

PROBLEM TO BE SOLVED: To provide: a metal particulate carrier produced using an environmentally-friendly polar solvent, particularly a water-based solvent through a simple process; a method for production of the carrier; and a catalyst comprising the metal particulate carrier by which an objective compound can be obtained at high efficiency in the reaction of an organic compound such as, hydration, oxidation, reduction or cross coupling. SOLUTION: The metal particulate carrier is obtained through supporting by a carrier comprising an inorganic or carbon material, of a metal particulate which has a bond of phenyl skeleton and metal M represented by formula (I) (wherein X1is (CH2)nCOOH or salt thereof, or a corresponding carboxylate ion (n=0 to 3); m is an integer of 1 to 5; and M is at least one metal selected from transition metals of groups 9, 10 and 11). COPYRIGHT: (C)2012,JPOandINPIT