354812-17-2 Usage
Uses
Used in Pharmaceutical Industry:
[2,3'-Bithiophene]-5-carboxamide, 4-aminois used as an anti-inflammatory agent for its ability to specifically block NF-kB-dependent gene expression, without affecting MAP kinase pathways. This makes it a potential candidate for the treatment of inflammatory diseases.
Used in Research Applications:
In research settings, [2,3'-Bithiophene]-5-carboxamide, 4-aminois used as a tool compound to study the role of IKK-2 in various cellular processes and signaling pathways. Its high selectivity and potency make it a valuable asset for investigating the underlying mechanisms of inflammation and other related conditions.
References
1) Kishore et al. (2003), A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts; J. Biol. Chem., 278 32861
Check Digit Verification of cas no
The CAS Registry Mumber 354812-17-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,4,8,1 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 354812-17:
(8*3)+(7*5)+(6*4)+(5*8)+(4*1)+(3*2)+(2*1)+(1*7)=142
142 % 10 = 2
So 354812-17-2 is a valid CAS Registry Number.
