354823-29-3

Upstream product

• 21740-23-8 3,5-O-bis(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride 

Downstream Products

• 961-07-9 2'-Deoxyguanosine 
• 958-09-8 2'-deoxy-D-adenosine 

Relevant academic research and scientific papers

Large-scale manufacturing of all four 2′-deoxynucleosides via novel strategies including a chemo-enzymatic process

A chemical synthesis of 2-deoxyribose-1-phosphate 2 and its enzymatic conversion into purine 2′-deoxynucleosides (dNus) are shown. Besides the chemoenzymatic process for purine dNus, a modified process for practical dC preparation is also established. Consequently, a series of practical manufacturing processes of all four dNus have been realized via novel strategies.