35490-10-9

Upstream product

• 186581-53-3 diazomethane 
• 7465-10-3 γ-(1-Hydroxy-1-cyclohexyl)-crotonsaeure 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 108-94-1 cyclohexanone 
• 623-43-8 crotonic acid methyl ester 

Downstream Products

• 69218-04-8 4-Nitro-benzenesulfonic acid 3-cyclohex-1-enylmethyl-4,4-dimethyl-pentyl ester 
• 69218-06-0 4-Nitro-benzenesulfonic acid 3-cyclohexylmethyl-4,4-dimethyl-pentyl ester 
• 69218-03-7 3-(Cyclohex-1'-enylmethyl)-4.4-dimethylpentan-1-ol 
• 69305-88-0 (E)-4-(Cyclohex-1'-enyl)-but-2-en-1-ol 
• 69218-01-5 (E)-4-(Cyclohex-1'-enyl)-but-2-ensaeuremethylester 

Relevant academic research and scientific papers

The chromium Reformatsky reaction: Access to adjacent quarternary centers

α-Bromo ketones, -esters and -nitriles react with chromium dichloride and ketones in a Barbier-type reaction to yield the kinetic crossed aldol products with one or two new quarternary centers. The reaction does not require special activation of the reage

REFORMATSKY REACTION USING Zn/Ag COUPLE

The Reformatsky reaction is easy to run in ethereal solvents in the presence of Zn/Ag couple.From methyl γ-bromocrotonate and krtones, remified esters are fromed in refluxing Et2O, linear ones in refluxing THF.