35509-80-9Relevant academic research and scientific papers
SYNTHESIS OF PYRROLIZINES BY INTRAMOLECULAR CAPURE OF 1,4-DIPOLAR INTERMEDIATES IN REACTIONS OF ENAMINES WITH DIMETHYL ACETYLENEDICARBOXYLATE
Verboom, W.,Visser, G. W.,Trompenaars, W. P.,Reinhoudt, D. N.,Harkema, S.,Hummel, G. J. van
, p. 3525 - 3533 (2007/10/02)
Solvent polarity and reaction temperature strongly influence the reactions of dimethyl acetylenedicarboxylate (DMAD) with 1-pyrrolidinyl enamines of acyclic and cyclic ketones.Whereas DMAD and 1-pyrrolidine (3) give only a
