3357-16-2

Basic information

• Product Name: 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one
• Synonyms: 5,5-Dimethyl-3-pyrrolidin-1-yl-cyclohex-2-enone; 5,5-Dimethyl-3-pyrrolidino-cyclohex-2-en-1-one; 5,5-Dimethyl-3-pyrrolidinocyclohex-2-enone
• CAS NO: 3357-16-2
• Molecular Formula: C₁₂H₁₉NO
• Molecular Weight: 193.2854
• Mol File: 3357-16-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 288.7°C at 760 mmHg
• Flash Point: 99.8°C
• Density: 1.038g/cm³
• Vapor Pressure: 0.00231mmHg at 25°C
• Refractive Index: 1.522
• CAS DataBase Reference: 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one(3357-16-2)
• EPA Substance Registry System: 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one(3357-16-2)

Safety Data

• Hazardous Substances Data: 3357-16-2(Hazardous Substances Data)

Usage

General Description

5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one is a chemical compound with a molecular formula of C14H21NO. It is a cyclic ketone with a pyrrolidine group attached to the third carbon atom of the cyclohexenone ring. 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one is used in organic synthesis and pharmaceutical research as a building block to create more complex molecules. It has the potential to exhibit biological activity and may be used in the development of new drugs or as a reference standard in analytical chemistry. The precise properties and uses of this chemical may vary depending on the specific application and context in which it is employed.

Upstream product

• 123-75-1 pyrrolidine 
• 126-81-8 dimedone 

Downstream Products

• 109507-69-9 1-(3-ethoxy-5,5-dimethyl-cyclohex-2-enylidene)-pyrrolidinium; bromide 
• 109477-06-7 N-(3-ethoxy-5,5-dimethyl-2-cyclohexen-1-ylidene)pyrrolidinium iodide 
• 80371-87-5 N-(3-methoxy-5,5-dimethyl-2-cyclohexen-1-ylidene)pyrrolidinium iodide 
• 55370-59-7 5,5-dimethyl-3-(4-methyl-benzoyl)-5,6-dihydro-4H-benzo[c]isoxazol-7-one 
• 55370-58-6 3-benzoyl-5,5-dimethyl-5,6-dihydro-4H-benzo[c]isoxazol-7-one 
• 76159-26-7 5,5-Dimethyl-2-piperidinomethyl-3-(1-pyrrolidinyl)-2-cyclohexen-1-on 
• 76159-27-8 5,5-Dimethyl-2-morpholinomethyl-3-(1-pyrrolidinyl)-2-cyclohexen-1-on 
• 126279-92-3 2-butanoyl-5,5-dimethyl-3-pyrrolidino-2-cyclohexen-1-one 
• 35509-80-9 5,5-dimethyl-7-oxo-3-(1-pyrrolidinyl)-2,8-cyclooctadiene-1,2-dicarboxylic acid dimethyl ester 
• 81239-29-4 4,4-dimethyl-6-oxo-2-(1-pyrrolidinyl)-1-cyclohexene-1-butenedioic acid dimethyl ester 
• 40710-50-7 4,5,5-trimethyl-3-pyrrolidin-1-yl-cyclohex-2-enone 
• 17450-95-2 5,5-dimethyl-2-butanoylcyclohexane-1,3-dione 
• 134223-91-9 3-pyrrolidino-5,5,6-trimethyl-2-cyclohexenone 
• 27361-25-7 3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione 

Relevant articles and documents

Rigid core vinamidinium salts and their N,N′-rotamers

The power of proton magnetic resonance spectroscopy to unravel stereochemical details is amply demonstrated. O-Methylation of 3-methylamino-5,5-dimethyl-2-cylohexen-1-one (1a) produces stable diastereomers, (Z)- and (E)-N-(3-methoxy-5,5-dimethyl-2-cyclohexen-1-ylidine)-N-methylaminium iodide (2a). As predicted by computation and confirmed by spectroscopy, the (Z)-vinylogous imidate salt predominates. Reaction of 2a with primary and secondary amines furnished a number of vinamidinium salts, including N-(3-methylamino-5,5-dimethyl-2-cyclohexen-1-ylidene)-N-methylaminium iodide (3a). Two rotamers of 3a were identified and characterized. A substantial number of additional compounds 2 and 3 are included in the study.

Chemistry of chelocardin. V. Condensation with amino reagents

-