3357-16-2

Usage

Uses

Used in Organic Synthesis:
5,5-Dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for the formation of various derivatives, which can be further utilized in the synthesis of pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one is used as a starting material for the development of new drugs. Its potential biological activity makes it a candidate for drug discovery, where it can be modified and optimized to target specific therapeutic areas.
Used as a Reference Standard in Analytical Chemistry:
5,5-Dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one can also be employed as a reference standard in analytical chemistry. Its defined structure and properties make it suitable for use in calibration of instruments, quality control, and method development in various analytical techniques.
The specific applications and properties of 5,5-dimethyl-3-(pyrrolidin-1-yl)cyclohex-2-en-1-one may vary depending on the context in which it is used, highlighting its adaptability across different fields within chemistry and related industries.

Upstream product

• 123-75-1 pyrrolidine 
• 126-81-8 dimedone 

Downstream Products

• 109507-69-9 1-(3-ethoxy-5,5-dimethyl-cyclohex-2-enylidene)-pyrrolidinium; bromide 
• 109477-06-7 N-(3-ethoxy-5,5-dimethyl-2-cyclohexen-1-ylidene)pyrrolidinium iodide 
• 80371-87-5 N-(3-methoxy-5,5-dimethyl-2-cyclohexen-1-ylidene)pyrrolidinium iodide 
• 126279-92-3 2-butanoyl-5,5-dimethyl-3-pyrrolidino-2-cyclohexen-1-one 
• 35509-80-9 5,5-dimethyl-7-oxo-3-(1-pyrrolidinyl)-2,8-cyclooctadiene-1,2-dicarboxylic acid dimethyl ester 
• 81239-29-4 4,4-dimethyl-6-oxo-2-(1-pyrrolidinyl)-1-cyclohexene-1-butenedioic acid dimethyl ester 
• 40710-50-7 4,5,5-trimethyl-3-pyrrolidin-1-yl-cyclohex-2-enone 
• 17450-95-2 5,5-dimethyl-2-butanoylcyclohexane-1,3-dione 
• 134223-91-9 3-pyrrolidino-5,5,6-trimethyl-2-cyclohexenone 
• 27361-25-7 3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione 
• 20129-56-0 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure 
• 132347-03-6 1-(5,5-dimethyl-3-pyrrolidino-cyclohex-2-enylidene)-pyrrolidinium; bromide 
• 132347-02-5 N-[3-(1'-pyrrolidino)-5,5-dimethyl-2-cyclohexen-1-ylidene]pyrrolidinium iodide 
• 80348-35-2 1-(3-ethylsulfanyl-5,5-dimethyl-cyclohex-2-enylidene)-pyrrolidinium; iodide 

Relevant academic research and scientific papers

Rigid core vinamidinium salts and their N,N′-rotamers

The power of proton magnetic resonance spectroscopy to unravel stereochemical details is amply demonstrated. O-Methylation of 3-methylamino-5,5-dimethyl-2-cylohexen-1-one (1a) produces stable diastereomers, (Z)- and (E)-N-(3-methoxy-5,5-dimethyl-2-cyclohexen-1-ylidine)-N-methylaminium iodide (2a). As predicted by computation and confirmed by spectroscopy, the (Z)-vinylogous imidate salt predominates. Reaction of 2a with primary and secondary amines furnished a number of vinamidinium salts, including N-(3-methylamino-5,5-dimethyl-2-cyclohexen-1-ylidene)-N-methylaminium iodide (3a). Two rotamers of 3a were identified and characterized. A substantial number of additional compounds 2 and 3 are included in the study.

Efficient synthesis of quinazolinones as intermediates of CNS agents via inverse-electron demand Diels-Alder reaction

Enaminones undergo inverse electron demand Diels-Alder reaction with 1,3,5-triazine, allowing access to functionalised quinazolinones as intermediates in the synthesis of CNS agents. This reaction is highly dependent of the solvent: 1,3,5-triazine undergo