3551-50-6

Basic information

• Product Name: Ethanethioic acid, S-[(1R,2R)-2-hydroxycyclopentyl] ester, rel- (9CI)
• Synonyms: Ethanethioic acid, S-[(1R,2R)-2-hydroxycyclopentyl] ester, rel- (9CI)
• CAS NO: 3551-50-6
• Molecular Formula: C7H12O2S
• Molecular Weight: 160.23
• Product Categories: CYCLOPENTANE
• Mol File: 3551-50-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 264.8°Cat760mmHg
• Flash Point: 113.9°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.00132mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: Ethanethioic acid, S-[(1R,2R)-2-hydroxycyclopentyl] ester, rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanethioic acid, S-[(1R,2R)-2-hydroxycyclopentyl] ester, rel- (9CI)(3551-50-6)
• EPA Substance Registry System: Ethanethioic acid, S-[(1R,2R)-2-hydroxycyclopentyl] ester, rel- (9CI)(3551-50-6)

Safety Data

• Hazardous Substances Data: 3551-50-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H12O2S/c1-5(8)10-7-4-2-3-6(7)9/h6-7,9H,2-4H2,1H3

Upstream product

• 285-67-6 Cyclopentene oxide 
• 507-09-5 thioacetic acid 
• 507-09-5 tiolacetic acid 
• 142-29-0 cyclopentene 
• 286-20-4 cyclohexene oxide 

Relevant articles and documents

Catalytic asymmetric synthesis of thiols

The synthesis of enantiopure thiols is of significant interest for industrial and academic applications. However, direct asymmetric approaches to free thiols have previously been unknown. Here we describe a novel organocascade that is catalyzed by a confined chiral phosphoric acid and furnishes O-protected β-hydroxythiols with excellent enantioselectivities. The method relies on an asymmetric thiocarboxylysis of meso-epoxides, followed by an intramolecular trans-esterification reaction. By varying the reaction conditions, the intermediate thioesters can also be obtained chemoselectively and enantioselectively.