35524-41-5 Usage
Description
1-(2-METHYLPHENYL)-1H-PYRROLE-2-CARBALDEHYDE, an organic compound with the chemical formula C13H11NO, is a yellowish solid derivative of pyrrole. It features a pyrrole ring with a 2-methylphenyl group at the 1 position and a carbaldehyde group at the 2 position. This structure and its reactivity render it a significant building block for the synthesis of pharmaceuticals and biologically active compounds.
Uses
Used in Pharmaceutical Industry:
1-(2-METHYLPHENYL)-1H-PYRROLE-2-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structure and reactivity, contributing to the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(2-METHYLPHENYL)-1H-PYRROLE-2-CARBALDEHYDE serves as a valuable compound for research purposes. Its properties allow scientists to explore its potential in creating novel biologically active molecules, which could lead to the discovery of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 35524-41-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,5,2 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35524-41:
(7*3)+(6*5)+(5*5)+(4*2)+(3*4)+(2*4)+(1*1)=105
105 % 10 = 5
So 35524-41-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO/c1-10-5-2-3-7-12(10)13-8-4-6-11(13)9-14/h2-9H,1H3
35524-41-5Relevant articles and documents
Construction of N-C Axial Chirality through Atroposelective C-H Olefination of N-Arylindoles by Palladium/Amino Acid Cooperative Catalysis
Zhang, Jitan,Xu, Qiaoqiao,Wu, Jiaping,Fan, Jian,Xie, Meihua
supporting information, p. 6361 - 6365 (2019/08/20)
Direct construction of N-C axial chirality via Pd-catalyzed atroposelective C-H olefination of N-arylindoles is reported. The crucial role of chiral amino acid as a cocatalyst in the regio- and stereocontrol has been disclosed. In this reaction, a wide range of arylindoles and functional alkenes could be well tolerated. Moreover, the practicality and synthetic value of this process were demonstrated by the divers and simple transformations of the products.
Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT 7 receptor ligands
Paillet-Loilier, Magalie,Fabis, Frederic,Lepailleur, Alban,Bureau, Ronan,Butt-Gueulle, Sabrina,Dauphin, Francois,Delarue, Catherine,Vaudry, Hubert,Rault, Sylvain
, p. 3753 - 3757 (2007/10/03)
Virtual screening studies have identified a series of phenylpyrroles as novel 5-HT7 receptor ligands. The synthesis and the affinity for the 5-HT7 receptor of these phenylpyrroles are described. Some of these compounds exhibited high affinity for the 5-HT7 receptors.
