35532-08-2

Basic information

• Product Name: 2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid
• Synonyms: 2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid;2-(4-carboxyphenyl)-1H-benzimidazole-6-carboxylic acid
• CAS NO: 35532-08-2
• Molecular Formula: C₁₅H₁₀N₂O₄
• Molecular Weight: 282.25
• Mol File: 35532-08-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid(35532-08-2)
• EPA Substance Registry System: 2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid(35532-08-2)

Safety Data

• Hazardous Substances Data: 35532-08-2(Hazardous Substances Data)

Usage

Molecular structure

2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid has a complex molecular structure with a benzene ring fused to an imidazole ring.

Class

It belongs to the class of benzimidazoles, which are heterocyclic compounds.

Functional groups

2-(4-Carboxyphenyl)-1H-benzimidazole-5-carboxylic acid has a carboxylic acid group attached to both the 2-position and the 5-position of the benzimidazole ring.

Substitution

A phenyl group is attached to the 4-position of the compound.

Potential applications

It may have applications in pharmaceuticals, materials science, and organic synthesis due to its unique structure and functional groups.

Further research

More research and experimentation is needed to reveal its specific properties and potential uses.

Upstream product

• 110336-03-3 2-(4-methoxycarbonyl-phenyl)-1⁽³⁾H-benzimidazole-5-carboxylic acid methyl ester 
• 459809-27-9 2-(4-methoxycarbonyl-phenyl)-3H-benzoimidazole-5-carboxylic acid 
• 619-66-9 4-Carboxybenzaldehyde 
• 619-05-6 3,4-diaminobenzoic acid 
• 99855-50-2 methyl 4-[ethoxy(imino)methyl]benzoate hydrochloride 
• 3987-92-6 methyl 4-amino-3-nitrobenzoate 
• 36692-49-6 Methyl 3,4-diaminobenzoate 
• 1129-35-7 4-cyanobenzoic acid methyl ester 

Downstream Products

• 459809-29-1 2-(4-Cyclohexylcarbamoyl-phenyl)-3H-benzoimidazole-5-carboxylic Acid 

Relevant articles and documents

Preferential Adsorption of CO2 in an Ultramicroporous MOF with Cavities Lined by Basic Groups and Open-Metal Sites

Here, we present a new ultramicroporous Cu2 paddlewheel based MOF. This ultramicroporous MOF has most of the features such as porosity (BET surface area = 945 m2/g), CO2 capacity (3.5 mmol/g at ambient temperature and pressure), CO2/N2 selectivity (sCO2/N2 = 250), and fast CO2 diffusion kinetics (Dc = 2.25 × 10-9 m2/s), comparable to some of the other high-performing ultramicroporous MOFs, with strong binding sites. Typically, such MOFs exhibit strong CO2-framework interactions (evidenced from a heat of adsorption ≥ 38 kJ/mol). However, the MOF explained here, despite having channels lined by the amine and the open-metal sites, possesses only a moderate CO2-framework interaction (HOA = 26 kJ/mol). Using periodic DFT, we have probed this counterintuitive observation.

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Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation

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Methods for the solid phase synthesis of combinatorial libraries of benzimidazol, benzoxazoles, benzothiazoles, and derivatives thereof

The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of compounds possessing these core structures, a general methodology for solid phase synthesis of these derivatives is provided. Arrays of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antiviral, antimicrobial, anticoagulant, and antiulcer activity, or use in the treatment of inflammation, hypertension, cancer, and other conditions can be prepared by this method.