355378-67-5

Upstream product

• 1840-19-3 1-isothiocyanato-3-trifluoromethyl-benzene 

Downstream Products

• 374589-08-9 1-(2-chloro-phenyl)-3-[5-mercapto-4-(3-trifluoromethyl-phenyl)-4H-[1,2,4]triazol-3-yl]-6-methyl-1H-pyridazin-4-one 

Relevant academic research and scientific papers

Synthesis and biological activity of 1,3,4-oxadiazole-substituted pyridazinones

Novel 3-(1,3,4-oxadiazol-2-yl)-1-aryl-6-methylpyridazin-4-ones have been synthesised by two methods. A preliminary bio-activity test showed that these compounds exhibit high antifungal activity.

Synthesis of pyridazinone-substituted 1,3,4-thiadiazoles, -1,3,4-oxadiazoles and -1,2,4-triazoles

Several 1-(1-aryl-1,4-dihydro-3-carboxy-6-methylpyridazin-4-one)-4-aryl thio-semicarbazides and their corresponding oxadiazole, thiadiazole and triazole derivatives were prepared and characterized by their spectral data. The preliminary biological tests showed that some new compounds exhibit good anti-fungal activity.