2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide, commonly known as chloramphenicol, is an antibiotic compound characterized by its ability to inhibit protein synthesis in bacteria, thereby preventing their growth and reproduction. It is effective against a broad spectrum of organisms, including both gram-positive and gram-negative bacteria. However, its use is limited due to the potential for serious side effects such as bone marrow suppression and aplastic anemia, making it a reserved option for severe infections that are resistant to other antibiotics.
35588-39-7
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Basic information
- Product Name: 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide
- Synonyms: 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide
- CAS NO:35588-39-7
- Molecular Formula: C8H7ClN2O4
- Molecular Weight: 230.606
- EINECS: N/A
- Product Categories: N/A
- Mol File: 35588-39-7.mol
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Chemical Properties
- Melting Point: 245°
- Boiling Point: 461.5°C at 760 mmHg
- Flash Point: 232.9°C
- Appearance: /
- Density: 1.599g/cm3
- Vapor Pressure: 3.86E-09mmHg at 25°C
- Refractive Index: 1.669
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide(CAS DataBase Reference)
- NIST Chemistry Reference: 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide(35588-39-7)
- EPA Substance Registry System: 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide(35588-39-7)
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Safety Data
- Hazard Codes: Xi
- Statements: 36
- Safety Statements: 26
- WGK Germany:
- RTECS:
- HazardClass: IRRITANT
- PackingGroup: N/A
- Hazardous Substances Data: 35588-39-7(Hazardous Substances Data)
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35588-39-7 Usage
Uses
Used in Pharmaceutical Industry:2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide is used as an antibiotic for the treatment of severe bacterial infections that are resistant to other antibiotics. Its broad-spectrum activity makes it a valuable option in cases where other treatments have failed or are unsuitable.
Used in Research and Development:
In the field of microbiology and pharmaceutical research, 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide serves as a reference compound for studying bacterial resistance mechanisms and the development of new antibiotics with novel mechanisms of action.
Used in Veterinary Medicine:
Although its use in human medicine is restricted, 2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide may still be employed in veterinary medicine for the treatment of bacterial infections in animals, where the risk-benefit analysis may be different.
Check Digit Verification of cas no
The CAS Registry Mumber 35588-39-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,5,8 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.Calculate Digit Verification of CAS Registry Number 35588-39:
(7*3)+(6*5)+(5*5)+(4*8)+(3*8)+(2*3)+(1*9)=147
147 % 10 = 7
So 35588-39-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClN2O4/c9-4-8(13)10-6-3-5(11(14)15)1-2-7(6)12/h1-3,12H,4H2,(H,10,13)
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2-Chloro-N-(2-hydroxy-5-nitrophenyl)acetamide
