356-30-9

Usage

Uses

Used in Pharmaceutical Industry:
5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione is used as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of novel drugs with enhanced properties. Its unique fluorinated structure allows for improved pharmacokinetics, bioavailability, and target specificity.
Used in Agrochemical Industry:
In the agrochemical sector, 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione serves as a building block for the production of fluorinated agrochemicals. Its incorporation into these compounds can enhance their effectiveness, stability, and environmental compatibility, leading to more sustainable agricultural practices.
Used in Specialty Chemicals Production:
5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione is utilized as an intermediate in the synthesis of specialty chemicals, which find applications in various industries such as coatings, adhesives, and lubricants. Its fluorinated nature imparts unique properties, including non-stick, water-repellent, and temperature-resistant characteristics.
Used in Polymer Synthesis:
5,5,6,6,7,7,7-HEPTAFLUOROHEPTANE-2,4-DIONE is employed as a monomer or co-monomer in the production of fluoropolymers, which exhibit exceptional chemical resistance, thermal stability, and low friction coefficients. These polymers are used in applications requiring high-performance materials, such as aerospace, automotive, and electronics industries.
Used in Cleaning and Degreasing Applications:
Due to its solvent properties, 5,5,6,6,7,7,7-Heptafluoroheptane-2,4-dione is used in cleaning and degreasing processes. Its ability to dissolve a wide range of substances, combined with its low toxicity and environmental impact, makes it an ideal choice for various industrial cleaning applications, including metal surface preparation and electronic component cleaning.

Upstream product

• 356-27-4 ethyl heptafluorobutyrate 
• 67-64-1 acetone 
• 115479-06-6 2-Acetyl-4,4,5,5,6,6,6-heptafluoro-3-oxo-hexanoic acid ethyl ester 
• 356-24-1 methyl heptafluorobutyrate 
• 70168-24-0 1,1,1,2,2,3,3-heptafluoro-4-aminohept-4-en-6-one 
• 86358-19-2 nonafluorobutyl-acetone 

Downstream Products

• 75823-64-2 3-Heptafluoropropyl-5-methyl-1H-pyrazole 
• 1312954-16-7 (Z)-5,5,6,6,7,7,7-heptafluoro-2-(2-{[(Z)-4,4,5,5,6,6,6-heptafluoro-1-methyl-3-oxo-1-hexenyl]amino}anilino)-2-hepten-4-one 
• 1312954-14-5 (Z)-2-(2-aminoanilino)-5,5,6,6,7,7,7-heptafluoro-2-hepten-4-one 

Relevant academic research and scientific papers

Reactions of perfluoroalkylacetones with nucleophilic reagents

The interaction of perfluoroalkylacetones of formula RFCH2COCH3 (RF=n-C3F7, n-C4F9, n-C6F13, n-C8F17) with ammonia and primary and secondary amines has been studied. In all cases, nucleophilic reagents initially dehydrofluorinate the starting ketone, and then substitution of the vinyl fluorine atom by a nucleophile occurs to give aza analogues of β-dicarbonyl compounds RFC(NR2)=CH-C(O)CH3; their hydrolysis yields the corresponding β-diketones under mild conditions. Perfluoroalkylacetones react with sodium alkoxides to give compounds of formula RFC(OR)2CH2COCH3, whose acidic hydrolysis also results in β-diketones.

Synthesis and reactions of the first fluoroalkylated 1,3- bis(trimethylsilyloxy)-1,3-butadienes

The first fluoroalkylated 1,3-bis(silyloxy)-1,3-butadienes have been prepared. Their reaction with oxalyl chloride provides a convenient approach to fluoroalkylated γ-alkylidenebutenolides.

Regioselective synthesis of 4-alkyl- and 4-aryl-6-(perfluoroalkyl)salicylic acid derivatives by formal [3+3] cyclocondensation of 1,3-bis(silyloxy)-1,3-butadienes with 3-silyloxy-1-(perfluoroalkyl)prop-2-en-1-ones

4-Alkyl- and 4-aryl-6-(perfluoroalkyl)salicylic acid derivatives were regioselectively prepared by [3+3] cyclization of 1,3-bis(silyl enol ethers) with 3-silyloxy-1-(perfluoroalkyl)prop-2-en-1-ones.

Synthese des F-alkylpyrazoles: Identification par RMN de 19F et comparaison avec les homologues hydrocarbones

In this paper, we report the synthesis of forty new pyrazoles substituted by one or more perfluoroalkyl chains.These compounds were obtained by condensation of a hydrazine (substituted or not) on an F-alkyl β-diketone.Unlike hydrocarbon chemistry, a react