356060-89-4Relevant academic research and scientific papers
A One-pot preparation of 1,3-diarylisobenzofuran
Hamura, Toshiyuki,Nakayama, Ryosuke
supporting information, p. 1013 - 1015 (2013/09/24)
A simple, practical, and efficient method for one-pot synthesis of symmetric and unsymmetrical 1,3-diarylisobenzofurans has been developed by sequential reactions of methyl 2-formylbenzoate with two identical or different aryl metal species.
A single-step synthesis of symmetrical 1,3-diarylisobenzofurans
Benderradji, Farah,Nechab, Malek,Einhorn, Cathy,Einhorn, Jacques
, p. 2035 - 2038 (2008/02/05)
A convenient single-step synthesis of various symmetrically substituted 1,3-diarylisobenzofurans from readily available 3-methoxy-3H-isobenzofuran-1-one (1a) and two equivalents of aryl Grignard reagents is described. The title compounds are obtained in medium to high isolated yields. Crude isobenzofuran has also been trapped by maleimide, furnishing pure Diels-Alder adduct almost quantitatively. Georg Thieme Verlag Stuttgart.
