356072-46-3 Usage
Uses
Used in Pharmaceutical Research:
SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE is used as a high-affinity, selective σ ligand for the development of novel therapeutic agents. Its unique binding properties to σ receptors can be leveraged to explore its potential in treating various neurological and psychiatric disorders, as well as other conditions where σ receptor modulation may be beneficial.
Used in Drug Discovery:
In the realm of drug discovery, SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE serves as a valuable lead compound. Its structural features and σ ligand properties can be further optimized and modified to develop more potent and selective drugs targeting specific σ receptor subtypes, thereby enhancing the therapeutic potential and reducing side effects.
Used in Chemical Synthesis:
SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE can also be utilized as a key intermediate in the synthesis of other complex organic molecules and pharmaceuticals. Its unique spiro structure and functional groups provide a versatile platform for chemical modifications, enabling the creation of a diverse range of compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 356072-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,0,7 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 356072-46:
(8*3)+(7*5)+(6*6)+(5*0)+(4*7)+(3*2)+(2*4)+(1*6)=143
143 % 10 = 3
So 356072-46-3 is a valid CAS Registry Number.
356072-46-3Relevant academic research and scientific papers
SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS
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Paragraph 117, (2020/03/15)
Compounds of formula (I) wherein A, R, L, Z, Q1, Q2 and n have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
Phenoxyalkylamine derivatives useful as opioid receptor agonists
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, (2008/06/13)
A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: wherein, X represents a group represented by the following general formula (II), (III), (IV), (V), or (VI), “A” represents a saturated or unsaturated 3- to 6-membered carbocyclic group and the like, “B” represents CH2 and the like, “n” represents 0 to 2, R1 represents a hydrogen atom, a halogen atom and the like, R2, R3, and R7 to R14 represent a hydrogen atom, a lower alkyl group which may be substituted and the like, R4 represents a hydrogen atom, a lower alkyl group which may be substituted and the like, R5 represents a hydrogen atom, a halogen atom and the like, R6 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, and R5 and R6, R7 and R8, R9 and R10, or R11 and R12 may bind to each other to form a cyclic structure.
