356073-59-1

Basic information

• Product Name: Benzenepropanol, a-(dichloromethyl)-a-(trifluoromethyl)-
• CAS NO: 356073-59-1
• Molecular Formula: C11H11Cl2F3O
• Molecular Weight: 287.109
• Mol File: 356073-59-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanol, a-(dichloromethyl)-a-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanol, a-(dichloromethyl)-a-(trifluoromethyl)-(356073-59-1)
• EPA Substance Registry System: Benzenepropanol, a-(dichloromethyl)-a-(trifluoromethyl)-(356073-59-1)

Safety Data

• Hazardous Substances Data: 356073-59-1(Hazardous Substances Data)

Upstream product

• 3277-89-2 phenethylmagnesium bromide 
• 126266-75-9 3,3-dichloro-1,1,1-trifluoroacetone 

Relevant articles and documents

Stereoselective generation of cis-2-lithio-3-CF3-oxirane via CF3-substituted β-oxido carbenoids. Highly stereoselective synthesis of CF3-substituted tri- and tetrasubstituted oxiranes and tetrasubstituted alkenes

Treatment of 2-substituted 3,3-dichloro-1,1,1-trifluoropropan-2-ols with organolithium reagents R2Li in THF at -98°C stereoselectively produces 2,3-disubstituted 2-lithio-3-trifluoromethyloxiranes with Li and CF3 cis. The reagents react with electrophiles El-X or organoboranes R3BR2 to give CF3-containing tri- and tetrasubstituted oxiranes or tetrasubstituted alkenes, respectively, with high diastereoselectivities.