35609-55-3

Upstream product

• 27266-61-1 benzhydryl 7-aminocephalosporanate 

Downstream Products

• 162252-95-1 (R)-3-Acetoxymethyl-8-oxo-7-[1-phenyl-meth-(E)-ylidene]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 162253-12-5 (R)-3-Acetoxymethyl-7-[1-bromo-meth-(E)-ylidene]-5,5,8-trioxo-5λ⁶-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 162252-93-9 benzhydryl 7-(dibromomethylene)cephalosporanate 
• 162253-01-2 (R)-3-Acetoxymethyl-7-[1-bromo-meth-(E)-ylidene]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 59128-53-9 benzhydryl 7-oxocephalosporanate 

Relevant academic research and scientific papers

Stille coupling approaches to the stereospecific synthesis of 7- [(E)- alkylidene]cephalosporins

Stille coupling methodology is used to stereospecifically synthesize 7- [(E)-alkylidene]cephalosporins, potential enzyme inhibitors which are unavailable via other synthetic methodology. Two procedures are described, utilizing either a stannylalkylidene c

Chphalosporin-derived mercaptans as inhibitors of serine and metallo-beta-lactamases

Compounds of formula I: See Formula I in Figures Section wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting s

A convenient method for the production of 6-oxopenicillinates and 7- oxocephalosporinates

A convenient and economical method for the preparation of 6- oxopenicillinates and 7-oxocephalosporinates from the corresponding amines is presented. These ketones are key intermediates in the synthesis of inhibitors of β-lactamase and elastase.