Stille coupling approaches to the stereospecific synthesis of 7- [(E)- alkylidene]cephalosporins

DOI: 10.1016/S0040-4039(98)02691-4

Source and publish data:

Tetrahedron Letters p. 1281 - 1284 (1999)

Update date:2022-07-29

Topics:

Authors:

Buynak, John D.

Doppalapudi, Venkata Ramana

Frotan, Mohammed

Kumar, Ramon

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Article abstract of DOI:10.1016/S0040-4039(98)02691-4

Stille coupling methodology is used to stereospecifically synthesize 7- [(E)-alkylidene]cephalosporins, potential enzyme inhibitors which are unavailable via other synthetic methodology. Two procedures are described, utilizing either a stannylalkylidene c

Full text of DOI:10.1016/S0040-4039(98)02691-4

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