35611-95-1

Basic information

• Product Name: 6-benzhydrylsulfanyl-7⁽⁹⁾H-purin-2-ylamine
• Synonyms: 6-benzhydrylsulfanyl-7⁽⁹⁾H-purin-2-ylamine
• CAS NO: 35611-95-1
• Molecular Weight: 333.417
• Mol File: 35611-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-benzhydrylsulfanyl-7⁽⁹⁾H-purin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzhydrylsulfanyl-7⁽⁹⁾H-purin-2-ylamine(35611-95-1)
• EPA Substance Registry System: 6-benzhydrylsulfanyl-7⁽⁹⁾H-purin-2-ylamine(35611-95-1)

Safety Data

• Hazardous Substances Data: 35611-95-1(Hazardous Substances Data)

Upstream product

• 154-42-7 thioguanin 
• 776-74-9 Bromodiphenylmethane 

Relevant articles and documents

Process for the preparation of purine derivatives

A process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof: STR1 which process comprises reacting a compound of formula (II): STR2 wherein the amino group is optionally protected, Y is iodo, optionally substituted benzylthio or (phenacylmethyl)thio, with a compound of formula (III): STR3 wherein Q is a leaving group, Rx and Ry are protected hydroxymethyl or acyloxymethyl, or group(s) convertible to hydroxymethyl or acyloxymethyl; and Rz is hydrogen or a group convertible thereto; and thereafter converting Y to X is hydroxy by means of hydrolysis, or to X is hydrogen by means of reduction; converting Rx and Ry when other than hydroxymethyl or acyloxymethyl, to hydroxymethyl or acyloxymethyl, optionally converting Rx /Ry hydroxymethyl to acyloxymethyl or vice versa, deprotecting the 2-amino group where necessary and converting Rz, (when other than hydrogen) to hydrogen; and optionally forming a pharmaceutically acceptable salt thereof.