35644-74-7

Upstream product

• 36616-60-1 (1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one 
• 6485-40-1 (R)-Carvone 
• 99-48-9 (4R,6R)-carveol 

Downstream Products

• 191410-13-6 1-((1R,3S,5R,6S)-5-Hydroxy-6-methyl-7-oxa-bicyclo[4.1.0]hept-3-yl)-ethanone 
• 1154606-95-7 tert-butyl{[(1R,2R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]hept-2-yl]oxy}diphenylsilane 
• 2102-58-1 (+)-trans-carveol 
• 1418734-55-0 (1R,3R)-2-methylene-5-(prop-1-en-2-yl)cyclohexane-1,3-diol 
• 1048013-51-9 (1R,2R,4S,6R)-1-methyl-2-(4-methoxybenzyloxy)-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptane 
• 1116113-16-6 (2R,6R)-(+)-1-phenylseleno-p-menth-8-en-2,6-diol 
• 1116113-15-5 (1S,2R,4S,6S)-(+)-6-phenylseleno-p-menth-8-en-1,2-diol 
• 633294-31-2 (1R,3R,5R)-1-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)-3-trimethylsilyloxy-2-methylenecyclohexane 
• 633294-28-7 (1R,3R,5R)-3-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)-2-methylenecyclohexanol 
• 633294-23-2 (1S,2R,4R,6R)-2-(tert-butyldimethylsilyloxy)-4-(tert-butyldiphenylsilyloxy)-1-methyl-7-oxabicyclo[4.1.0]heptane 
• 57429-67-1 3,5-dinitrobenzoate ester of (+)-trans-carveol 

Relevant academic research and scientific papers

Enantioselective approach to the synthesis of cyclohexane carbocyclic nucleosides

(R)-(-)-Carvone was used as starting material for the synthesis of a new series of 2-(hydroxymethyl)-cyclohexane-1,3-diol nucleosides. The enantioselective precursors of the nucleoside analogues were obtained via a stereo- and regioselective hydroboration reaction. The compounds have equatorial oriented base moieties despite the presence of three other axial substituents.

VITAMIN D RECEPTOR ACTIVATORS AND METHODS OF MAKING

The invention relates to compounds that are vitamin D receptor activators, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.

Epoxidation of allylic alcohols in aqueous solutions of non surfactant amphiphilic sugars

A variety of cyclic and acyclic allylic alcohols undergo efficient chemo-, regio- and/or stereoselective epoxidations in neutral aqueous solutions of amphiphilic carbohydrates (sucrose, L-arabinose, methyl or ethyl β-D-fructopyranoside) by using dilute hydrogen peroxide in the presence of molybdic or tungstic salts.

(R)-Carvone as chiral template for the synthesis of some polyols

Some (4S,6R,7R) 4,6,7-trihydroxyheptyl derived building blocks have been obtained from (R)-carvone as the chiral template.A key-step is the Baeyer-Villiger oxidation of a suitable intermediate.

Synthesis of the four epimeric tosylates of (5R)-2,3-epoxy-5-isopropenyl-cyclohexanol

Described is the synthesis of the four optically pure epoxytosylates 5, 6, 9 and 12, each with four chiral centers determined, from a single starting material, (R)(-) carvone.

Efficient Enantiospecific Synthesis of Key A-Ring Synthons for the Preparation of 1α,25-Dihydroxyvitamin D3 Using a Chromium((II)-Mediated Reaction

Key A-ring synthons for the synthesis of 1α,25-dihydroxyvitamin D3 have been prepared efficiently from (R)-(-)-carvone by use of diastereoselective chromium(II)-mediated addition of an allylic halide to an aldehyde as a key step.