(1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol

Base Information

• Chemical Name: (1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol
• CAS No.: 35644-74-7
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.236
• Mol file: 35644-74-7.mol

Synonyms:(1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol

Chemical Property of (1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol

There total 9 articles about (1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one (36616-60-1) → trans-1,2-Epoxy-p-menth-8-en-6-ol (13944-75-7,24120-79-4,31750-20-6,33318-22-8,35644-74-7,35692-59-2,39903-74-7,39903-81-6,39903-82-7,128385-82-0)

Guidance literature:

With sodium tetrahydroborate; cerium(III) chloride; In methanol; for 1h; Ambient temperature;

Reference yield: 30.0%

(1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one (36616-60-1) → trans-1,2-Epoxy-p-menth-8-en-6-ol (13944-75-7,24120-79-4,31750-20-6,33318-22-8,35644-74-7,35692-59-2,39903-74-7,39903-81-6,39903-82-7,128385-82-0) + (1S,2S,4S,6R)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-ol (35692-59-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 24h; Ambient temperature;

DOI:10.1080/00397919508011466

Reference yield:

(4R,6R)-carveol (99-48-9,1197-06-4,1197-07-5,2102-58-1,2102-59-2,5157-78-8,5503-11-7,7632-16-8,18383-51-2,22567-18-6,20307-86-2) → (1R,2R,4S,6S)-(-)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-ol (24120-79-4) + (R)-Carvone (6485-40-1,2244-16-8) + (1S,2R,4S,6R)-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol (35644-74-7)

Guidance literature:

With L-arabinose; dihydrogen peroxide; molybdic acid; In phosphate buffer; at 2 ℃; for 24h; pH=7; Further Variations:; Reagents; time; Product distribution;

DOI:10.1039/b108352j

upstream raw materials:

(1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one

(R)-Carvone

(4R,6R)-carveol

Downstream raw materials:

1-((1R,3S,5R,6S)-5-Hydroxy-6-methyl-7-oxa-bicyclo[4.1.0]hept-3-yl)-ethanone

tert-butyl{[(1R,2R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]hept-2-yl]oxy}diphenylsilane

(2R,6R)-(+)-1-phenylseleno-p-menth-8-en-2,6-diol

(1S,2R,4S,6S)-(+)-6-phenylseleno-p-menth-8-en-1,2-diol