356519-34-1

Basic information

• Product Name: (2S)-1-(2-nitrobenzene-1-sulfonyl) aziridine-2-carboxylic acid
• Synonyms: (2S)-1-(2-nitrobenzene-1-sulfonyl) aziridine-2-carboxylic acid
• CAS NO: 356519-34-1
• Molecular Weight: 272.238
• Mol File: 356519-34-1.mol

Chemical Properties

• CAS DataBase Reference: (2S)-1-(2-nitrobenzene-1-sulfonyl) aziridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-(2-nitrobenzene-1-sulfonyl) aziridine-2-carboxylic acid(356519-34-1)
• EPA Substance Registry System: (2S)-1-(2-nitrobenzene-1-sulfonyl) aziridine-2-carboxylic acid(356519-34-1)

Safety Data

• Hazardous Substances Data: 356519-34-1(Hazardous Substances Data)

Upstream product

• 2731-73-9 (S)-3-chloroalanine 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 1758-77-6 (2S)-2-aziridinecarboxylic acid 

Downstream Products

• 389806-02-4 (S)-2-(2-nitro-benzenesulfonyl)-aziridine-2-carboxylic acid tert-butyl ester 
• 356519-32-9 (S)-2-[N-(2-nitrobenzenesulfonyl)amino]-6-(N-benzylamino)-6-methyl-4-heptynoic acid 
• 365549-24-2 (S)-2-(2-nitrobenzenesulfonamido)-6-dibenzylamino-6-methyl-4-heptic acid 

Relevant articles and documents

PROCESSES FOR PREPARING OPTICALLY ACTIVE AMINO ACID DERIVATIVES

An optically active amino acid derivative is produced by N-protecting an optically active 3-haloalanine derivative followed by cyclization, or cyclizing this derivative followed by N-protection to thereby give an optically active N-protected-aziridine-2-carboxylic acid derivative which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent, or by N-protecting an optically active 3-haloalanine derivative to thereby give N-protected-aziridine-2-carboxylic acid which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent. According to this process, natural and unnatural optically active amino acids can be produced from inexpensive materials by using simple procedures.