Cas 356535-47-2,4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2<i>H</i>-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester

356535-47-2

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Product Name: 4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester
Synonyms: 4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester
CAS NO:356535-47-2
Molecular Formula:
Molecular Weight: 1042.85
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
NIST Chemistry Reference: 4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester(356535-47-2)
EPA Substance Registry System: 4-oxo-pentanoic acid 2-[[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-(2-cyano-ethylsulfanyl)-phosphoryloxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl ester(356535-47-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 356535-47-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 356535-47-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,5,3 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 356535-47:
(8*3)+(7*5)+(6*6)+(5*5)+(4*3)+(3*5)+(2*4)+(1*7)=162
162 % 10 = 2
So 356535-47-2 is a valid CAS Registry Number.

356535-47-2Upstream product

356535-47-2Downstream Products

356535-47-2Relevant academic research and scientific papers

An approach to the desulfurization of oligonucleotide phosphorothioates

Reese, Colin B.,Yan, Hongbin

, p. 2501 - 2504 (2007/10/03)

Protected oligonucleotide phosphorothioates are converted by a two-step procedure into oligonucleotides with standard phosphodiester internucleotide linkages. The remaining protecting groups are then removed by ammonolysis.

Solution phase synthesis of ISIS 2922 (Vitravene) by the modified H-phosphonate approach

Reese, Colin B.,Yan, Hongbin

, p. 2619 - 2633 (2007/10/03)

The synthesis of Vitravene, a 21-mer oligonucleotide phosphorothioate (d[Gp(s)Cp(s)Gp(s)Tp(s)Tp(s)Tp(s)Gp(s)Cp(s)-Tp(s)Cp(s)Tp(s)Tp(s)Cp(s)Tp(s)Tp(s)C p(s)Tp(s)Tp(s)Gp(s)Cp(s)G]) by the modified H-phosphonate approach in solution is reported. The syntheti

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