356561-08-5

Usage

Uses

Used in Organic Synthesis:
5-IODO-4-METHYL-PYRIDIN-2-YLAMINE is used as a key intermediate for the synthesis of various organic compounds, leveraging its unique structure and reactivity.
Used in Pharmaceuticals:
In the pharmaceutical industry, 5-IODO-4-METHYL-PYRIDIN-2-YLAMINE is used as a building block for the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Agrochemicals:
5-IODO-4-METHYL-PYRIDIN-2-YLAMINE is employed as a component in the formulation of agrochemicals, such as pesticides and herbicides, due to its chemical properties that can be tailored for specific applications in agriculture.
Used in Dyestuffs:
In the dyestuffs industry, 5-IODO-4-METHYL-PYRIDIN-2-YLAMINE is used as a precursor for the production of dyes, taking advantage of its chemical structure to create a range of colors and properties in dye formulations.

InChI:InChI=1/C6H7IN2/c1-4-2-6(8)9-3-5(4)7/h2-3H,1H3,(H2,8,9)

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 

Downstream Products

• 550347-54-1 2-chloro-5-iodo-4-methylpyridine 
• 1262336-89-9 4-methyl-5-iodopyridin-2-yl 4-methylbenzenesulfonate 
• 1575831-12-7 1-(6'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-1'H-spiro[azetidine-3,3'-furo[3,4-c]pyridine]-1-yl)-2-(methylsulfonyl)ethanone 
• 1575837-05-6 tert-butyl 6'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-1'H-spiro[azetidine-3,3'-furo[3,4-c]pyridine]-1-carboxylate 
• 1575837-07-8 6'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-1'H-spiro[azetidine-3,3'-furo[3,4-c]pyridine] trifluoroacetic acid salt 

Relevant academic research and scientific papers

Synthesis of bridged analogs of epibatidine. 3-Chloro-5,7,8,9,9a,10-hexahydro-7,10-methanopyrrolo[1,2-b]-2,6-naphthyridine and 2-chloro-5,5a,6,7,8,10-hexahydro-5,8-methanopyrrolo[2,1-b]-1,7-naphthyridine

The synthesis of conformationally locked analogs of epibatidine are described in which the key step is an intramolecular reductive palladium-catalyzed Heck-type coupling.

SPIROCYCLIC ISOXAZOLINES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic isoxazoline derivatives of Formula (1) stereoisomers thereof, veterinary or pharmaceutical acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables

Remarkable switch in the regiochemistry of the iodination of anilines by N-iodosuccinimide: Synthesis of 1,2-dichloro-3,4-diiodobenzene

Direct iodination of anilines by NIS in polar solvents (such as DMSO) affords p-iodinated products with up to >99% regioselectivity. Switching to less polar solvents (such as benzene) in the presence of AcOH inverts this outcome toward dramatically increased or preferential generation of the o-isomers, also with up to >99% regioselectivity. This finding was exploited in the synthesis of 1,2-dichloro-3,4-diiodobenzene. Georg Thieme Verlag Stuttgart - New York.

5-ALKYNYL-PYRIMIDINES

The present invention encompasses compounds of general formula (1) wherein R1 to R4 R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

5-ALKYNYL-PYRIMIDINES

The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS

The present invention encompasses compounds of general formula (1) wherein R1 to R4 R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine

Epibatidine analogues 3-5, possessing the pyridine ring fused to the 2,3 position of the 7-azabicyclo[2.2.1]heptane ring, and analogue 8a, possessing a benzene ring fused to the 5,6 position, were synthesized by procedures involving key steps of trapping

Synthesis of conformationally constrained spirodihydrofuropyridine analogues of epibatidine

Conformationally constrained spirofuropyridine analogues of epibatidine, syn-2 and anti-2, in which the 7-azabicyclo[2.2.1]heptane system and the 2-chloropyridine ring are held rigidly with the shorter and longer N-N distances, respectively, were synthesized from N-Boc-7-azabicyclo[2.2.1]heptan-2-one. The preliminary binding studies suggested that syn-2 has stronger binding affinity for nAChRs than anti-2.

Compounds and methods for promoting smoking cessation

Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.