35674-56-7 Usage
Description
2-Benzylisoquinolinium chloride is a quaternary ammonium salt featuring a benzyl group attached to an isoquinoline ring. It is frequently utilized in organic synthesis and pharmaceutical research as a precursor for synthesizing benzylisoquinoline alkaloids, which are natural products with a wide range of biological activities.
Uses
Used in Pharmaceutical Research:
2-Benzylisoquinolinium chloride is used as a precursor in the synthesis of benzylisoquinoline alkaloids for their diverse biological activities and potential therapeutic applications.
Used in Organic Synthesis:
It is used as a versatile chemical building block in the development of new organic compounds and materials.
Used in Cardiac Research:
2-Benzylisoquinolinium chloride is used as a potential antiarrhythmic agent due to its interactions with cardiac ion channels, contributing to the study and treatment of heart rhythm disorders.
Used in Neurotransmitter Receptor Research:
It serves as a pharmacological tool for investigating the structure and function of certain neurotransmitter receptors in the central nervous system, aiding in the understanding and development of treatments for neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 35674-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,7 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 35674-56:
(7*3)+(6*5)+(5*6)+(4*7)+(3*4)+(2*5)+(1*6)=137
137 % 10 = 7
So 35674-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H14N.ClH/c1-2-6-14(7-3-1)12-17-11-10-15-8-4-5-9-16(15)13-17;/h1-11,13H,12H2;1H/q+1;/p-1
35674-56-7Relevant articles and documents
Hoveyda–Grubbs catalysts with an N→Ru coordinate bond in a six-membered ring. Synthesis of stable, industrially scalable, highly efficient ruthenium metathesis catalysts and 2-vinylbenzylamine ligands as their precursors
Polyanskii, Kirill B.,Alekseeva, Kseniia A.,Raspertov, Pavel V.,Kumandin, Pavel A.,Nikitina, Eugeniya V.,Gurbanov, Atash V.,Zubkov, Fedor I.
supporting information, p. 769 - 779 (2019/04/17)
A novel and efficient approach to the synthesis of 2-vinylbenzylamines is reported. This involves obtaining 2-vinylbenzylamine ligands from tetrahydroisoquinoline by alkylation and reduction followed by the Hofmann cleavage. The resultant 2-vinylbenzyl-amines allowed us to obtain new Hoveyda–Grubbs catalysts, which were thoroughly characterised by NMR, ESIMS, and X-ray crystallography. The utility of this chemistry is further demonstrated by the tests of the novel catalysts (up to 10?2 mol %) in different metathesis reactions such as cross metathesis (CM), ring-closing metathesis (RCM) and ring-opening cross metathesis (ROCM).
