356780-33-1

Basic information

• Product Name: [1,2,4]Triazol-1-yl-acetic acid [1-(2-bromo-phenyl)-meth-(E)-ylidene]-hydrazide
• CAS NO: 356780-33-1
• Molecular Weight: 308.137
• Mol File: 356780-33-1.mol

Chemical Properties

• CAS DataBase Reference: [1,2,4]Triazol-1-yl-acetic acid [1-(2-bromo-phenyl)-meth-(E)-ylidene]-hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2,4]Triazol-1-yl-acetic acid [1-(2-bromo-phenyl)-meth-(E)-ylidene]-hydrazide(356780-33-1)
• EPA Substance Registry System: [1,2,4]Triazol-1-yl-acetic acid [1-(2-bromo-phenyl)-meth-(E)-ylidene]-hydrazide(356780-33-1)

Safety Data

• Hazardous Substances Data: 356780-33-1(Hazardous Substances Data)

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 56563-02-1 2-(1H-1,2,4-triazol-1-yl)acetohydrazide 

Relevant articles and documents

Synthesis of 5-arylidene-2-aryl-3-(1, 2, 4-triazoloacetamidyl)-1, 3-thiadiazol-4-ones as antibacterial, antifungal, analgesic and diuretic agents

1, 2, 4-Triazole on reaction with ethyl chloroacetate affords 1, 2, 4-triazoloacetate 1 which on treatment with hydrazine hydrate yields (acetohydrazido)-1, 2, 4-triazole 2. Condensation of 2 with various substituted aromatic aldehydes affords arylideneacetohydrazido-1, 2, 4-triazoles 3 which on cycloaddition with mercaptoacetic acid gives 2-(substituted aryl)-3-(1, 2, 4-triazolylacetamidyl)-4-oxo-thiazolidines 4. Treatment of the 4-thiazolidinones with various substituted aromatic aldehydes affords 5-arylidene-2-aryl-3-(1, 2, 4-trizolylacetamidyl)-1, 3-thiazolidin-4-ones 5. Their structures have been elucidated on the basis of their elemental analysis and spectral data. All the products have been screened for their antibacterial, antifungal, analgesic and diuretic activities.