356785-82-5Relevant academic research and scientific papers
Inhibitors of the bacterial cell wall biosynthesis enzyme MurC
Reck, Folkert,Marmor, Stephen,Fisher, Stewart,Wuonola, Mark A.
, p. 1451 - 1454 (2007/10/03)
A series of phosphinate transition-state analogues of the L-alanine adding enzyme (MurC) of bacterial peptidoglycan biosynthesis was prepared and tested as inhibitors of the Escherichia coli enzyme. Compound 4 was identified as a potent inhibitor of MurC
