35684-24-3Relevant academic research and scientific papers
Base-Promoted Amidation and Esterification of Imidazolium Salts via Acyl C-C bond Cleavage: Access to Aromatic Amides and Esters
Karthik, Shanmugam,Muthuvel, Karthick,Gandhi, Thirumanavelan
, p. 738 - 751 (2019/01/24)
Imidazolium salts have been effectively employed as suitable acyl transfer agents in amidation and esterification in organic synthesis. The weak acyl C(O)-C imidazolium bond was exploited to generate acyl electrophiles, which further react with amines and alcohols to afford amides and esters. The broad substrate scope of anilines and benzylic amines and base-promoted conditions are the benefits of this route. Interestingly, phenol, benzylic alcohols, and a biologically active alcohol can also be subjected to esterification under the optimized conditions.
Hexabromoacetone as tribromoacetylating agent of alcohols and amines and as mediator in the conversion of carboxylic acids into amides in the presence of triphenylphosphine
Menezes, Fabrício G.,Kolling, Rosane,Bortoluzzi, Adaílton J.,Gallardo, Hugo,Zucco, César
body text, p. 2559 - 2561 (2009/08/09)
Hexabromoacetone has been used as an alternative tribromoacetylating agent of primary alcohols and amines and as mediator in the conversion of carboxylic acids into amides in the presence of triphenylphosphine. The reactions have been performed under mild conditions with moderate to good yields. All the products have been adequately characterized by their physical and spectroscopic properties.
Combination of the topliss approach with the Free-Wilson analysis in the study of antimycobacterial activity of 4-alkylthiobenzanilides
Kunes, Jiri,Jachym, Jiri,Jirasko, Petr,Odlerova, Zelmira,Waisser, Karel
, p. 1503 - 1510 (2007/10/03)
On the basis of a preliminary study of the antimycobacterial activity of thiobenzanilides, a group of 4′-isopropyl- and 4′-butylthiobenzanilides have been synthesized and tested against Mycobacterium tuberculosis, Mycobacterium kansasii, Mycobacterium avi
