35686-75-0Relevant academic research and scientific papers
APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF
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, (2019/04/09)
Described herein are ASK1 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of blood disease, autoimmune disorders, pulmonary disorders, hypertension, inflammatory diseases, fibrotic diseases, diabetes, diabetic nephropathy, renal diseases, respiratory diseases, cardiovascular diseases, acute lung injuries, acute or chronic liver diseases, and neurodegenerative diseases.
ASK1 INHIBITING AGENTS
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Page/Page column 171; 184-185, (2018/09/08)
Provided are compounds of Formulas (I'), (I), (II') and (II), or pharmaceutically acceptable salts thereof, and methods for their use and production.
Alkylacetylene substituted Acyltryptophanols
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Page/Page column 84, (2009/02/10)
The present invention relates to acyltryptophanols of the general formula I, in which R1, R2, R3, Q and X have the meaning as defined in the description. The compounds according to the invention are effective FSH antagonists and can be used for example fo
BICYCLIC ACYLTRYPTOPHANOLS
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Page/Page column 90, (2008/12/06)
The present invention relates to acyltryptophanols of the general formula (I), in which Q, V, X, W, R1, R2, R3, R4, R5, R6, R7 and R8 have the meaning as defined in the description. The compounds according to the invention are effective FSH antagonists and can be used for example for fertility control in men or in women, or for the prevention and/or treatment of osteoporosis.
