35688-18-7 Usage
Uses
Used in Scientific Research:
N-(methylsulfonyl)glycine is used as an analytical reagent for various scientific studies and experiments. Its unique chemical properties make it a valuable tool in the analysis and identification of different substances.
Used in Chemical Synthesis:
In the chemical industry, N-(methylsulfonyl)glycine is used as an intermediate in the synthesis of other organic compounds. Its amine and sulfone functional groups provide a versatile platform for further chemical reactions and the creation of new molecules.
Used in Pharmaceutical Development:
N-(methylsulfonyl)glycine is employed in the pharmaceutical sector as a potential candidate for drug development. Its chemical structure may offer new avenues for the treatment of various diseases and conditions, although further research is required to fully understand its potential applications.
Used in Environmental Applications:
N-(methylsulfonyl)glycine may also find use in environmental applications, such as water treatment or soil remediation, due to its water solubility and chemical reactivity. It could potentially be used to remove contaminants or improve the quality of environmental samples.
Safety Precautions:
It is important to handle N-(methylsulfonyl)glycine with care, as it can cause skin and eye irritation. Inhalation or ingestion of N-(methylsulfonyl)glycine may also have harmful effects. Always refer to the safety data sheet for detailed information on potential hazards and recommended handling procedures to ensure safe use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 35688-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,8 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 35688-18:
(7*3)+(6*5)+(5*6)+(4*8)+(3*8)+(2*1)+(1*8)=147
147 % 10 = 7
So 35688-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H7NO4S/c1-9(7,8)4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
35688-18-7Relevant academic research and scientific papers
Structure-Reactivity Studies on the Equilibrium Reaction between Phenolate Ions and 2-Aryloxazolin-5-ones: Data Consistent with a Concerted Acyl-Group-Transfer Mechanism
Curran, Terence C,Farrar, Charles R.,Niazy, Omima,Williams, Andrew
, p. 6828 - 6837 (2007/10/02)
The rate and equilibrium constants for the reaction between phenolate anions and 2-aryloxazolin-5-ones have been measured as a function of the structures Ar and Ar'.The change in "effective" charge on both phenol-leaving oxygen and endocyclic oxygen from ground to transition state, as determined from the relevant Broensted parameters, is substantial and essentially additive consistent with a concerted displacement mechanism.The stepwise mechanism requires a small change in effective charge on the phenol oxygen because departure of phenolate ion from the tetrahedral intermediate cannot be rate limiting.Hydroxide ion attack on the C-5 atom of the oxazolinone to yield a benzoylglycine has a Hammett ?- dependence which can only arise from a concerted displacement; the rate-limiting step for the stepwise mechanism is the addition of hydroxide and the transition state of the rate-limiting step will therefore not involve much endocyclic C-O bond fission.An inverse deuterium oxide solvent isotope effect indicates that the observed general-acid catalysis has a specific-acid/nucleophilic mechanism; both hydroxide and oxonium ion catalysis are demonstrated by using 18O-labeling experiments to involve nucleophilic attack at the carbonyl (C-5) center.The equilibrium constant for reaction of azide ion with 2-phenyloxazolin-5-ones has been measured; it is suggested that the absence of racemization during azide coupling in peptide synthesis is related to the very unfavorable equilibrium constant for oxazolinone formation compared with that of activated oxygen esters.
