35709-09-2

Basic information

• Product Name: CIS-9-OCTADECENYL METHANESULFONATE
• Synonyms: methanesulfonate,(z)-9-octadecen-1-o;OLEYL METHANE SULFATE;METHANESULFONIC ACID OLEYL ESTER;CIS-9-OCTADECENYL METHANESULFONATE;oleyl methanesulphonate;oleyl mesylate;(Z)-9-Octadecen-1-ol methanesulfonate;[(Z)-Octadec-9-enyl] methanesulfonate
• CAS NO: 35709-09-2
• Molecular Formula: C₁₉H₃₈O₃S
• Molecular Weight: 346.57
• EINECS: 252-686-8
• Product Categories: Aliphatics,Glycerols, Fatty Acid Derivatives & Lipids, Sulfur & Selenium Compounds
• Mol File: 35709-09-2.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 465.7°Cat760mmHg
• Flash Point: 235.4°C
• Appearance: /
• Density: 0.954g/cm³
• Vapor Pressure: 2.1E-08mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: −20°C
• CAS DataBase Reference: CIS-9-OCTADECENYL METHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-9-OCTADECENYL METHANESULFONATE(35709-09-2)
• EPA Substance Registry System: CIS-9-OCTADECENYL METHANESULFONATE(35709-09-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 35709-09-2(Hazardous Substances Data)

Usage

Uses

Oleyl Mesylate, is a derivative of Oleyl Alcohol (O235935), which can be used a nonionic surfactant, emulsifier, emollient and thickener in skin creams, lotions and many other cosmetic products. This compound can also be used in the synthesis of lipidic alcohols and amines.

InChI:InChI=1/C19H38O3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22-23(2,20)21/h10-11H,3-9,12-19H2,1-2H3/b11-10+

Upstream product

• 143-28-2 oleoyl alcohol 
• 124-63-0 methanesulfonyl chloride 
• 60-29-7 diethyl ether 
• 19788-74-0 cis-10-nonadecenoic acid methyl ester 
• 112-62-9 Methyl oleate 

Downstream Products

• 593-31-7 rac-1-(Z-9-octadecenyl)glycerol 
• 150844-25-0 1-O-(4-methoxybenzyl)-2-O-methyl-3-O-(cis-9-octadecenyl)-sn-glycerol 
• 150844-23-8 1,6-di-O-(cis-9-octadecenyl)-2,5-di-O-methyl-3,4-bis-O-(4-methoxybenzyl)-D-mannitol 
• 22297-32-1 1-[(triphenylcarbinyl)oxy]-2,3-bis[(Z)-octadec-9-enyloxy]propane 
• 291312-49-7 2-(9-octadecenyl)-1,3-benzylideneglycerol 
• 104162-47-2 DODMA 
• 926652-61-1 dioleyloxybenzaldehyde 
• 1189331-85-8 (5R)-4-benzyl-5-oleyloxymethyl-[1,3,4]-oxathiazinane-3,3-dioxide 
• 1189332-05-5 (5S)-4-benzyl-5-oleyloxymethyl-[1,3,4]-oxathiazinane-3,3-dioxide 
• 40165-68-2 di((Z)-octadec-9-enyl)amine 
• 7173-65-1 methyl di((Z)-octadec-9-enyl)amine 
• 1346224-29-0 (3R,4R)-1-benzyl-3,4-bis((Z)-octadec-9-enyloxy)pyrrolidine 
• 112-90-3 (Z)-9-octadecen-1-amine 
• 1138782-12-3 N,N-dimethyl-3,4-dioleyloxybenzylamine 

Relevant articles and documents

Enantiomeric synthesis of natural alkylglycerols and their antibacterial and antibiofilm activities

Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs (5l–5n) were synthesised in enantiomerically pure form, and were characterised for the first time together with 12 other known and naturally occurring AKGs (5a–5k, 5o). Their structures were established using 1H and 13C APT NMR with 2D-NMR, ESI-MS or HRESI-MS and optical rotation data, and they were tested for their antibacterial and antibiofilm activities. AKGs 5a–5m and 5o showed activity against five clinical isolates and P. aeruginosa ATCC 15442, with MIC values in the range of 15–125 μg/mL. In addition, at half of the MIC, most of the AKGs reduced S. aureus biofilm formation in the range of 23%–99% and P. aeruginosa ATCC 15442 biofilm formation in the range of 14%–64%. The antibiofilm activity of the AKGs assessed in this work had not previously been studied.

COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS

The disclosure features amino lipids and compositions involving the same. Nanoparticle compositions include an amino lipid as well as additional lipids such as phospholipids, structural lipids, PEG lipids, or a combination thereof. Nanoparticle compositions further including therapeutic and/or prophylactic agents such as RNA are useful in the delivery of therapeutic and/or prophylactic agents to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

MANUFACTURING METHOD OF CATIONIC LIPID

PROBLEM TO BE SOLVED: To provide a manufacturing method of industrial cationic lipid capable of efficiently providing high purity cationic lipid without needs for special facility. SOLUTION: A cationic lipid represented by the formula (2) is obtained by mixing cationic lipid represented by the formula (1) and a tetraalkylammonium salt having X- in an organic solvent, filtering deposited tetraalkylammonium iodide to obtain a filtrate and concentrating the filtrate to deposit tetraalkylammonium iodide. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT