35709-40-1Relevant academic research and scientific papers
COMPOSES SULFURES HETEROCYCLIQUES. XCVI. REACTION DE L'HYDRAZINE SUR LES DIHYDRO-1,2 BENZOTHIAZINE-3,1 THIONES-4
Legrand, Louis,Lozac'H, Noel
, p. 139 - 143 (2007/10/02)
1-Alkyl-1,2-dihydro-3,1-benzothiazine-4-thiones 1, when reacting with hydrazine, give with a good yield a 1-alkyl-3-amino-2,3-dihydro-1H-quinazoline-4-thione-2, often together with a derivative of 1,3,4-thiadiazole-3. With 1-aryl-1,2-dihydro-3,1-benzothiazine-4-thiones, the main product of the reaction with hydrazine appears to be a 1-aryl-4-hydrazono-1,4-dihydro-2H-3,1-benzothiazine 4, sometimes with some amount of 3.On the contrary, when reacting with hydrazine, 1-alkyl (or 1-aryl)-1,2-dihydro-3,1-benzothiazin-4-ones lead to a 2-alkylamino (or arylamino)-benzohydrazide 5. By thermolysis 4 isomerizes into 2 which is accompanied by derivatives (3 and 7) of 1,3,4-thiadiazole.The structures of compounds 2, 4 and 7 have been studied by NMR and UV spectrometry.
The Preparation of Some 2-Nitroacridines and Related Compounds
Rosevear, Judi,Wilshire, John F. K.
, p. 839 - 853 (2007/10/02)
The reaction of 2-fluoro-5-nitrobenzaldehyde with a wide variety of arylamines gives, in general, mixtures of the corresponding 2-arylamino-5-nitrobenzaldehydes and their related anils.Both aldehydes and anils readily underwent acid-catalysed cyclization to give the corresponding 2-nitroacridines.The effect of substituent on the rate of cyclization of these aldehydes and of some related anilino-benzaldehydes and -acetophenones has been studied in trifluoroacetic acid solution by means of 1H n.m.r. spectroscopy.A solution of 2-(N-methylanilino)-5-nitrobenzaldehydein trifluoroacetic acid appears to contain a substituted acridinium ion; treatment of this solution with alkali gave 10-methyl-2-nitroacridone. 1H n.m.r. data for a wide variety of substituted 2-nitroacridines are discussed.
Synthetic Applications of Intramolecular Insertion in Arylcarbenes. V. o-Benzyl, Phenylamino, Phenoxy and Phenylthio Phenylcarbenes
Crow, Wilfrid D.,McNab, Hamish
, p. 1037 - 1050 (2007/10/02)
The 2-(XC6H4)-substituted phenylcarbenes in which X = CH2, NH, O and S have been generated and pyrolysed in the gas phase at low pressure.When X = CH2 or NH, the main reaction is simple insertion into the adjacent o-position of the XC6H5 ring to give dihydroanthracenes and dihydroacridines respectively.The use of substituents shows that no spiro diene rearrangement is involved in the case X = NH.For X = O or S, on the other hand, the carbene inserts into the ?-system of the XC6H5 ring and expansion occurs to give benzocycloheptafurans and thiophens.
