62152-50-5

Upstream product

• 59303-95-6 N-(p-tolyl)anthranilic acid p-toluenesulfonylhydrazide 
• 49604-73-1 ethyl 2-(4-tolylamino)benzoate 
• 16524-23-5 N-p-tolyl-anthranilic acid 
• 90-02-8 salicylaldehyde 
• 16634-82-5 N-(p-tolyl)-2-chloroacetamide 
• 106-49-0 p-toluidine 
• 271-58-9 anthranil 
• 5720-05-8 4-methylphenylboronic acid 
• 35709-40-1 N-(p-tolyl)anthranilic acid hydrazide 
• 624-31-7 4-tolyl iodide 
• 529-23-7 o-aminobenzaldehyde 

Downstream Products

• 16524-23-5 N-p-tolyl-anthranilic acid 
• 613-15-0 2-methylacridine 

Relevant academic research and scientific papers

Rigid four-nitrogen four-tooth fourth subgroup metal complex and application thereof

The invention provides a rigid tetra-nitrogen four-tooth fourth subgroup metal complex, which has the structure shown in the formula (I): wherein n is 2 - 4. R Is C1 - C30 alkyl, C6 - C30 aryl or substituted aryl of C6 - C30. X Is a halogen, C1 - C30 alky

Copper-Catalyzed Electrophilic Amination of Arylboronic Acids with Anthranils: An Access to N-Aryl-2-aminophenones

An efficient copper-catalyzed electrophilic amination strategy has been established for the rapid synthesis of N-aryl-2-aminophenones from readily available arylboronic acids/esters and anthranils. This protocol features good functional group tolerance, broad substrate scope, and operational simplicity. Moreover, a tandem C-H borylation and C-N coupling protocol has also been developed to transform simple arenes to the valuable N-aryl-2-aminophenones in one pot. Additionally, the synthetic potential of this methodology is further demonstrated by the synthesis of various useful N-heterocycles and derivatives.

Tertiary amine self-catalyzed intramolecular Csp3-H functionalization with in situ generated allenes for the formation of 3-alkenyl indolines

A novel methodology for the synthesis of 3-alkenyl indolines through the reaction of in situ generated allenes with N-benzylic Csp3-H has been developed. The reaction was realized by Pd(0) catalyzed allenylation of propargyl carbonate with organoboron and subsequent tertiary amine self-catalyzed Csp3-H functionalization in a one-pot process. Control reactions suggested that the substrate itself might also serve as a Lewis base for the N-benzylic Csp3-H functionalization.

An Expedient Process for the Synthesis of 2-(N -Arylamino)benzaldehydes from 2-Hydroxybenzaldehydes via Smiles Rearrangement

This paper describes an efficient Smiles rearrangement process for the synthesis of 2-(N-arylamino)benzaldehyde derivatives with reasonable yields. A mechanism is proposed for the reaction course. Georg Thieme Verlag Stuttgart, New York.

The Preparation of Some 2-Nitroacridines and Related Compounds

The reaction of 2-fluoro-5-nitrobenzaldehyde with a wide variety of arylamines gives, in general, mixtures of the corresponding 2-arylamino-5-nitrobenzaldehydes and their related anils.Both aldehydes and anils readily underwent acid-catalysed cyclization to give the corresponding 2-nitroacridines.The effect of substituent on the rate of cyclization of these aldehydes and of some related anilino-benzaldehydes and -acetophenones has been studied in trifluoroacetic acid solution by means of 1H n.m.r. spectroscopy.A solution of 2-(N-methylanilino)-5-nitrobenzaldehydein trifluoroacetic acid appears to contain a substituted acridinium ion; treatment of this solution with alkali gave 10-methyl-2-nitroacridone. 1H n.m.r. data for a wide variety of substituted 2-nitroacridines are discussed.