357177-90-3

Basic information

• Product Name: N-(3,4-Dimethoxyphenylethyl)-3,4-methylenedioxycinnamamide
• Synonyms: N-(3,4-Dimethoxyphenylethyl)-3,4-methylenedioxycinnamamide
• CAS NO: 357177-90-3
• Molecular Weight: 355.39
• Mol File: 357177-90-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(3,4-Dimethoxyphenylethyl)-3,4-methylenedioxycinnamamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-Dimethoxyphenylethyl)-3,4-methylenedioxycinnamamide(357177-90-3)
• EPA Substance Registry System: N-(3,4-Dimethoxyphenylethyl)-3,4-methylenedioxycinnamamide(357177-90-3)

Safety Data

• Hazardous Substances Data: 357177-90-3(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 2373-80-0 3,4-(methylenedioxy)cinnamic acid 
• 1426294-41-8 diisopropyl (2-((3,4-dimethoxyphenethyl)amino)-2-oxoethyl)phosphonate 
• 123-46-6 girard's reagent T 

Downstream Products

• 156488-61-8 3-(3,4-methylenedioxyphenyl)-N-(3,4-dimethoxyphenethyl)propionamide 

Relevant articles and documents

Biomimetic Total Synthesis of Dysoxylum Alkaloids

A five-step total synthesis of Dysoxylum alkaloids has been achieved using a biomimetic approach from zanthoxylamide protoalkaloids. The synthesis featured a direct amidation and a Bischler-Napieralski reaction to form the dihydroisoquinoline ring, which

Column chromatography-free solution-phase synthesis of a natural piper-amide-like compound library

We have achieved an efficient solution-phase parallel synthesis of a library of natural piper-amide-like compounds from the bifunctional β-phosphono-N-hydroxy-succinimidyl ester intermediate. The primary important feature in our study is the construction of natural-product-like molecules through the adaptation of sophisticated organic reactions that create water-soluble byproducts for a chromatography-free purification. This simple and efficient method rapidly provides a combinatorial library of high yield and purity. The library was evaluated against GPCR targets to demonstrate its potential use as a tool for drug discovery and in chemical biology.