357289-94-2Relevant academic research and scientific papers
Synthesis of substituted piperidines, decahydroquinolines and octahydroindolizines by radical rearrangement reactions of 2-alkylideneaziridines
Prévost, Natacha,Shipman, Michael
, p. 7165 - 7175 (2007/10/03)
Rearrangement of a variety of 3-(2-methyleneaziridin-1-yl)propyl radicals, generated using Bu3SnH/AIBN by homolytic cleavage of phenylselenide substituted 2-methyleneaziridines, produces 3-methylenepiperidines in yields ranging from 58 to 68%.
Intramolecular radical rearrangement reactions of 2-methyleneaziridines: Application to the synthesis of substituted piperidines, decahydroquinolines, and octahydroindolizines
Prevost, Natacha,Shipman, Michael
, p. 2383 - 2385 (2007/10/03)
(matrix presented) Intramolecular 5-exo cyclization of 3-(2-methyleneaziridin-1-yl)propyl radicals leads to the generation of a highly strained, bicyclic aziridinylcarbinyl radical that undergoes C-N bond fission to the ring-expanded aminyl radical. This
